β-Catenin Regulates Cardiac Energy Metabolism in Sedentary and Trained Mice.

Wnt/β-catenin signaling glucose metabolism lipid metabolism oxidative phosphorylation training-induced heart hypertrophy β-oxidation

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
17 Dec 2020
Historique:
received: 15 11 2020
revised: 10 12 2020
accepted: 16 12 2020
entrez: 22 12 2020
pubmed: 23 12 2020
medline: 23 12 2020
Statut: epublish

Résumé

The role of canonical Wnt signaling in metabolic regulation and development of physiological cardiac hypertrophy remains largely unknown. To explore the function of β-catenin in the regulation of cardiac metabolism and physiological cardiac hypertrophy development, we used mice heterozygous for cardiac-specific

Identifiants

pubmed: 33348907
pii: life10120357
doi: 10.3390/life10120357
pmc: PMC7766208
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Grant of President of Ukraine for Gifted Youth
ID : № 50/4.3 from 01.08.2014
Organisme : National Academy of Sciences of Ukraine
ID : N40/2015-2020
Organisme : National Science Centre, Poland
ID : UMO-2014/13/B/NZ4/00199, UMO-2016/22/E/NZ4/00650, UMO-2017/27/N/NZ4/01995 and UMO-2015/17/D/NZ5/03446
Organisme : European Union's Horizon 2020 research and innovation program under Marie Sklodowska-Curie
ID : 665735 (Bio4Med)
Organisme : Polish Ministry of Science and Higher Education
ID : 3548/H2020/COFUND/2016/2

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Auteurs

Volodymyr V Balatskyi (VV)

Department of Human Genetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Akademika Zabolotnogo Street, 03680 Kyiv, Ukraine.
Laboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.

Oksana L Palchevska (OL)

Department of Human Genetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Akademika Zabolotnogo Street, 03680 Kyiv, Ukraine.
Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology in Warsaw, 46580 Warsaw, Poland.

Lina Bortnichuk (L)

Department of Human Genetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Akademika Zabolotnogo Street, 03680 Kyiv, Ukraine.

Ana-Maria Gan (AM)

Laboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.

Anna Myronova (A)

Department of Human Genetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Akademika Zabolotnogo Street, 03680 Kyiv, Ukraine.

Larysa L Macewicz (LL)

Department of Human Genetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Akademika Zabolotnogo Street, 03680 Kyiv, Ukraine.

Viktor O Navrulin (VO)

Laboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.

Lesya V Tumanovska (LV)

Department of General and Molecular Pathophysiology, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4 Bogomoletz Street, 01024 Kyiv, Ukraine.

Adam Olichwier (A)

Laboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.

Pawel Dobrzyn (P)

Laboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.

Oksana O Piven (OO)

Department of Human Genetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Akademika Zabolotnogo Street, 03680 Kyiv, Ukraine.

Classifications MeSH