Evaluation of the diagnostic accuracy of a new point-of-care rapid test for SARS-CoV-2 virus detection.
COVID-19
/ diagnosis
COVID-19 Nucleic Acid Testing
/ methods
Early Diagnosis
Humans
Italy
/ epidemiology
Limit of Detection
Pandemics
Point-of-Care Systems
/ standards
Prospective Studies
Reference Standards
Retrospective Studies
SARS-CoV-2
/ genetics
Sensitivity and Specificity
Translational Research, Biomedical
COVID-19
Health surveillance
Point-of-care rapid test
SARS-CoV-2
Journal
Journal of translational medicine
ISSN: 1479-5876
Titre abrégé: J Transl Med
Pays: England
ID NLM: 101190741
Informations de publication
Date de publication:
21 12 2020
21 12 2020
Historique:
received:
19
10
2020
accepted:
30
11
2020
entrez:
22
12
2020
pubmed:
23
12
2020
medline:
31
12
2020
Statut:
epublish
Résumé
The easy access to a quick diagnosis of coronavirus disease 2019 (COVID-19) is a key point to improve the management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to contain its spread. Up to now, laboratory real-time PCR is the standard of care, but requires a fully equipped laboratory and significant infrastructure. Consequently, new diagnostic tools are required. In the present work, the diagnostic accuracy of the point-of-care rapid test "bKIT Virus Finder COVID-19" (Hyris Results obtained with the Hyris Kit are the same as that of standard laboratory-based real time PCR methods for all the analyzed samples. In addition, the Hyris Kit provides the test results in less than 2 h, a significantly shorter time compared to the reference methods, without the need of a fully equipped laboratory. To conclude, the Hyris kit represents a promising tool to improve the health surveillance and to increase the capacity of SARS-CoV-2 testing.
Sections du résumé
BACKGROUND
The easy access to a quick diagnosis of coronavirus disease 2019 (COVID-19) is a key point to improve the management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to contain its spread. Up to now, laboratory real-time PCR is the standard of care, but requires a fully equipped laboratory and significant infrastructure. Consequently, new diagnostic tools are required.
METHODS
In the present work, the diagnostic accuracy of the point-of-care rapid test "bKIT Virus Finder COVID-19" (Hyris
RESULTS
Results obtained with the Hyris Kit are the same as that of standard laboratory-based real time PCR methods for all the analyzed samples. In addition, the Hyris Kit provides the test results in less than 2 h, a significantly shorter time compared to the reference methods, without the need of a fully equipped laboratory.
CONCLUSIONS
To conclude, the Hyris kit represents a promising tool to improve the health surveillance and to increase the capacity of SARS-CoV-2 testing.
Identifiants
pubmed: 33349261
doi: 10.1186/s12967-020-02651-y
pii: 10.1186/s12967-020-02651-y
pmc: PMC7752099
doi:
Types de publication
Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
488Références
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