High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature.

Adenoid cystic carcinoma Case report High grade transformation Minor salivary glands Palate

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 24 11 2020
revised: 05 12 2020
accepted: 05 12 2020
pubmed: 23 12 2020
medline: 23 12 2020
entrez: 22 12 2020
Statut: ppublish

Résumé

Adenoid cystic carcinoma (ACC) is a rare tumor developed in minor salivary glands, the palate being the most common site. Here, we report a case of a 58-year-old man with a 3-year-growing swelling in the right palate diagnosed with high grade transformation adenoid cystic carcinoma. The exam revealed a 4 cm large mass. A tumor resection with a radical neck dissection was performed. High grade transformation in adenoid cystic carcinoma is recently described by Cheuk et al. in 1999. This transformation has more aggressive behavior than conventional solid ACC and has usually been associated with recurrences, early distant metastasis, and greater mortality. The aim here is to highlight clinical, histopathological, therapeutic and prognostic aspects of high-grade transformation in ACC with literature review.

Identifiants

DOI: 10.1016/j.ijscr.2020.12.014 PMID: 33352446 PMC: PMC7753240
pubmed: 33352446
pii: S2210-2612(20)31203-7
doi: 10.1016/j.ijscr.2020.12.014
pmc: PMC7753240
pii:
doi:

Types de publication

Case Reports

Langues

eng

Pagination

162-166

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Bchir Ahlem (B)

Department of Pathology, Fattouma Bourguiba University Hospital of Monastir, 5000, Tunisia; Faculty of Medecine, University of Monastir, 5000, Tunisia. Electronic address: bchirahlem1@gmail.com.

Njima Manel (N)

Department of Pathology, Fattouma Bourguiba University Hospital of Monastir, 5000, Tunisia; Faculty of Medecine, University of Monastir, 5000, Tunisia. Electronic address: manelnjima@yahoo.fr.

Ben Abdeljalil Nouha (BA)

Department of Pathology, Fattouma Bourguiba University Hospital of Monastir, 5000, Tunisia; Faculty of Medecine, University of Monastir, 5000, Tunisia. Electronic address: nouhaba@yahoo.fr.

Ben Hammouda Seiffeddine (BH)

Department of Pathology, Fattouma Bourguiba University Hospital of Monastir, 5000, Tunisia; Faculty of Medecine, University of Monastir, 5000, Tunisia. Electronic address: seif.hammouda91@gmail.com.

Mighri Khalifa (M)

Faculty of Medecine, University of Monastir, 5000, Tunisia; Department of Head and Neck, Tahar Sfar University Hospital of Mahdia, 5100, Tunisia. Electronic address: rosaly_tunisie@hotmail.com.

Njim Leila (N)

Department of Pathology, Fattouma Bourguiba University Hospital of Monastir, 5000, Tunisia; Faculty of Medecine, University of Monastir, 5000, Tunisia. Electronic address: njiml@yahoo.fr.

Zakhama Abdelfateh (Z)

Department of Pathology, Fattouma Bourguiba University Hospital of Monastir, 5000, Tunisia; Faculty of Medecine, University of Monastir, 5000, Tunisia. Electronic address: abdel.zakhama@topnet.tn.

Classifications MeSH