The Retinal Vessel Density as a New Vascular Biomarker in Multisystem Involvement in Fabry Disease: An Optical Coherence Tomography Angiography Study.
Fabry disease
TSVDS
echocardiography
left atrial volume index
optical coherence tomography angiography
peak arterial pulmonary pressure
retinal vessel density
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
18 Dec 2020
18 Dec 2020
Historique:
received:
30
11
2020
revised:
11
12
2020
accepted:
16
12
2020
entrez:
23
12
2020
pubmed:
24
12
2020
medline:
24
12
2020
Statut:
epublish
Résumé
In this study, we evaluated the possible relationship between the changes in retinal vessel density (VD) by optical coherence tomography angiography (OCTA) and the vascular alterations involving renal, cardiovascular and central nervous systems in patients affected by Fabry disease (FD). In 50 FD patients, the retinal superficial capillary plexus (SCP) and deep capillary plexus (DCP) in macular region were evaluated by OCTA examination. The patients also underwent a brain magnetic resonance imaging scan, renal and echocardiographic examinations with quantification of systolic pulmonary arterial pressure (PAPs) and left atrial volume index (LAVi). The VD of SCP and DCP was inversely related with E/e' ratio, LAVi, interventricular septal thickness, global longitudinal strain (GLS) and PAPs (
Identifiants
pubmed: 33352849
pii: jcm9124087
doi: 10.3390/jcm9124087
pmc: PMC7766384
pii:
doi:
Types de publication
Journal Article
Langues
eng
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