Transient Receptor Potential Vanilloid 6 (TRPV6) Proteins Control the Extracellular Matrix Structure of the Placental Labyrinth.

Biological Transport Biomarkers Calcium / metabolism Cell Movement / genetics Cell Survival / genetics Computational Biology Extracellular Matrix / metabolism Female Gene Knockdown Techniques Humans Placenta / metabolism Pregnancy Proteolysis Proteome Proteomics TRPV Cation Channels / genetics
FND3A HTRA1 TRPV6 calcium homeostasis extracellular matrix fibronectin granzyme nano LC–MS/MS placenta trophoblast

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
18 Dec 2020
Historique:
received: 20 11 2020
revised: 11 12 2020
accepted: 15 12 2020
entrez: 23 12 2020
pubmed: 24 12 2020
medline: 17 3 2021
Statut: epublish

Résumé

Calcium-selective transient receptor potential Vanilloid 6 (TRPV6) channels are expressed in fetal labyrinth trophoblasts as part of the feto-maternal barrier, necessary for sufficient calcium supply, embryo growth, and bone development during pregnancy. Recently, we have shown a less- compact labyrinth morphology of

Identifiants

DOI: 10.3390/ijms21249674 PMID: 33352987 PMC: PMC7767235
pubmed: 33352987
pii: ijms21249674
doi: 10.3390/ijms21249674
pmc: PMC7767235
pii:
doi:

Substances chimiques

Biomarkers 0
Proteome 0
TRPV Cation Channels 0
Calcium SY7Q814VUP

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : FE629/2 WE4866/1-1 SFB894/P2
Organisme : University of the Saarland
ID : HOMFOR for CFT

Références

Front Immunol. 2017 Apr 24;8:467
pubmed: 28484462
Arch Med Sci. 2013 Aug 30;9(4):690-6
pubmed: 24049530
Nat Rev Genet. 2001 Jul;2(7):538-48
pubmed: 11433360
Mol Hum Reprod. 2001 Dec;7(12):1133-42
pubmed: 11719590
Dev Biol. 2014 Aug 1;392(1):62-79
pubmed: 24803182
Dev Dyn. 2005 Jul;233(3):1102-9
pubmed: 15861393
Dev Biol. 2006 Oct 15;298(2):498-513
pubmed: 16904100
J Chem Theory Comput. 2005 Nov;1(6):1286-97
pubmed: 26631672
Dev Biol. 2015 Jan 1;397(1):89-102
pubmed: 25446274
Biochim Biophys Acta Mol Cell Res. 2018 Nov;1865(11 Pt B):1815-1829
pubmed: 30798946
J Invest Dermatol. 1981 Mar;76(3):181-9
pubmed: 7240787
J Cell Sci. 2006 Dec 15;119(Pt 24):5011-4
pubmed: 17158907
Biol Reprod. 2002 Nov;67(5):1473-9
pubmed: 12390878
J Immunol. 1998 Sep 15;161(6):2772-9
pubmed: 9743335
Dev Biol. 2005 Aug 1;284(1):12-24
pubmed: 15963972
Sci Signal. 2011 May 03;4(171):ra27
pubmed: 21540454
Am J Med Genet A. 2018 Sep;176(9):1950-1955
pubmed: 30144375
FEMS Microbiol Rev. 2011 Jan;35(1):147-200
pubmed: 20695902
J Biol Chem. 2006 Mar 10;281(10):6124-9
pubmed: 16377621
Am J Hum Genet. 2018 Jun 7;102(6):1104-1114
pubmed: 29861107
Stem Cells. 2016 Nov;34(11):2648-2660
pubmed: 27334848
Biochem J. 2003 Apr 1;371(Pt 1):39-48
pubmed: 12513693
BMC Med Genet. 2020 Mar 30;21(1):64
pubmed: 32228492
Front Immunol. 2019 May 01;10:960
pubmed: 31118936
Sci Rep. 2019 Sep 16;9(1):13383
pubmed: 31527654
J Biol Chem. 2013 Jun 7;288(23):16629-44
pubmed: 23612980
Cureus. 2020 Feb 15;12(2):e7000
pubmed: 32206464
J Cell Sci. 2002 Oct 15;115(Pt 20):3861-3
pubmed: 12244123
Dev Biol. 2002 Oct 15;250(2):358-73
pubmed: 12376109
J Endocr Soc. 2019 Jan 03;3(3):602-606
pubmed: 30820485
Bone. 2005 Sep;37(3):323-36
pubmed: 15993670
J Biol Chem. 2001 Jun 1;276(22):19461-8
pubmed: 11278579
Biol Reprod. 2009 Mar;80(3):415-24
pubmed: 19038858
Electrophoresis. 2004 May;25(9):1327-33
pubmed: 15174055
J Bone Miner Res. 2019 Apr;34(4):699-710
pubmed: 30786075
Nat Rev Immunol. 2003 May;3(5):361-70
pubmed: 12766758
Obstet Gynecol. 1979 Jan;53(1):74-6
pubmed: 760023
Curr Opin Immunol. 2003 Oct;15(5):544-52
pubmed: 14499263
Pflugers Arch. 2007 Jul;454(4):523-33
pubmed: 17334777
Placenta. 2012 Nov;33(11):919-26
pubmed: 22964307
J Biol Chem. 2012 May 25;287(22):17930-41
pubmed: 22427671
Biol Chem. 2006 Jul;387(7):827-37
pubmed: 16913832
J Bone Miner Res. 2008 Aug;23(8):1249-56
pubmed: 18348695
J Exp Med. 1983 Jun 1;157(6):1844-54
pubmed: 6854210
Biochem Cell Biol. 2014 Dec;92(6):441-8
pubmed: 25372600
Reprod Sci. 2019 Apr;26(4):532-542
pubmed: 29909746
J Vis Exp. 2012 Jan 08;(59):e3202
pubmed: 22257865
Lab Invest. 2009 Nov;89(11):1195-220
pubmed: 19770840
Placenta. 2012 Dec;33(12):1036-8
pubmed: 23083999
Anal Chem. 2003 Sep 1;75(17):4646-58
pubmed: 14632076
J Cell Sci. 1981 Apr;48:19-34
pubmed: 7276088
Placenta. 2010 Feb;31(2):126-33
pubmed: 20022372

Auteurs

Manuel Winter (M)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Petra Weissgerber (P)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.
Transgenic Technologies, Center for Molecular Signaling (PZMS), Saarland University, Building 61.4, 66421 Homburg, Germany.

Karolin Klein (K)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Femke Lux (F)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.
Transgenic Technologies, Center for Molecular Signaling (PZMS), Saarland University, Building 61.4, 66421 Homburg, Germany.

Daniela Yildiz (D)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.
Zentrum für Human- und Molekularbiologie (ZHMB) and Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Ulrich Wissenbach (U)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Stephan E Philipp (SE)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.
ORCID: 0000-0003-1959-9167

Markus R Meyer (MR)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Veit Flockerzi (V)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Claudia Fecher-Trost (C)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Transport biologique › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Phénomènes physiologiques › Mouvement cellulaire › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Sciences de l'information › Informatique › Biologie informatique › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace extracellulaire › Matrice extracellulaire › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ciblage de gène › Techniques de knock-down de gènes › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Structures de l'embryon › Placenta › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Métabolisme › Protéolyse › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéome › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Biochimie › Protéomique › Transient Receptor Potential Vanilloid 6...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Canaux cationiques TRPV › Transient Receptor Potential Vanilloid 6...