2020 EULAR points to consider for the prevention, screening, assessment and management of non-adherence to treatment in people with rheumatic and musculoskeletal diseases for use in clinical practice.


Journal

Annals of the rheumatic diseases
ISSN: 1468-2060
Titre abrégé: Ann Rheum Dis
Pays: England
ID NLM: 0372355

Informations de publication

Date de publication:
06 2021
Historique:
received: 27 08 2020
revised: 23 10 2020
accepted: 26 10 2020
pubmed: 24 12 2020
medline: 28 6 2022
entrez: 23 12 2020
Statut: ppublish

Résumé

Non-adherence to treatment could preclude reaching an optimal outcome. Thirty to 80% of patients with rheumatic and musculoskeletal diseases (RMDs) do not adhere to the agreed treatment. The objective was to establish points to consider (PtCs) for the prevention, screening, assessment and management of non-adherence to (non-)pharmacological treatments in people with RMDs. An EULAR task force (TF) was established, and the EULAR standardised operating procedures for the development of PtCs were followed. The TF included healthcare providers (HCPs), comprising rheumatologists, nurses, pharmacists, psychologists, physiotherapists, occupational therapists and patient-representatives from 12 European countries. A review of systematic reviews was conducted in advance to support the TF in formulating the PtCs. The level of agreement among the TF was established by anonymous online voting. Four overarching principles and nine PtCs were formulated. The PtCs reflect the phases of action on non-adherence. HCPs should assess and discuss adherence with patients on a regular basis and support patients to treatment adherence. As adherence is an agreed behaviour, the treatment has to be tailored to the patients' needs. The level of agreement ranged from 9.5 to 9.9 out of 10. These PtCs can help HCPs to support people with RMDs to be more adherent to the agreed treatment plan. The basic scheme being prevent non-adherence by bonding with the patient and building trust, overcoming structural barriers, assessing in a blame-free environment and tailoring the solution to the problem.

Sections du résumé

BACKGROUND
Non-adherence to treatment could preclude reaching an optimal outcome. Thirty to 80% of patients with rheumatic and musculoskeletal diseases (RMDs) do not adhere to the agreed treatment.
OBJECTIVES
The objective was to establish points to consider (PtCs) for the prevention, screening, assessment and management of non-adherence to (non-)pharmacological treatments in people with RMDs.
METHODS
An EULAR task force (TF) was established, and the EULAR standardised operating procedures for the development of PtCs were followed. The TF included healthcare providers (HCPs), comprising rheumatologists, nurses, pharmacists, psychologists, physiotherapists, occupational therapists and patient-representatives from 12 European countries. A review of systematic reviews was conducted in advance to support the TF in formulating the PtCs. The level of agreement among the TF was established by anonymous online voting.
RESULTS
Four overarching principles and nine PtCs were formulated. The PtCs reflect the phases of action on non-adherence. HCPs should assess and discuss adherence with patients on a regular basis and support patients to treatment adherence. As adherence is an agreed behaviour, the treatment has to be tailored to the patients' needs. The level of agreement ranged from 9.5 to 9.9 out of 10.
CONCLUSIONS
These PtCs can help HCPs to support people with RMDs to be more adherent to the agreed treatment plan. The basic scheme being prevent non-adherence by bonding with the patient and building trust, overcoming structural barriers, assessing in a blame-free environment and tailoring the solution to the problem.

Identifiants

pubmed: 33355152
pii: annrheumdis-2020-218986
doi: 10.1136/annrheumdis-2020-218986
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

707-713

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: TAS has received grant/research support from AbbVie, and Roche, has been consultant for AbbVie, Sanofi Genzyme, and has been paid speaker for AbbVie, Roche and Sanofi. DA has received grant/research support from AbbVie, Amgen, Celgene, Lilly, Medac, Merck, Novartis, Pfizer, Roche, Sandoz, Sanofi Genzyme and UCB, has been consultant for AbbVie, Amgen, Celgene, Lilly, Medac, Merck, Novartis, Pfizer, Roche, Sandoz, Sanofi Genzyme and UCB and has been paid speaker for AbbVie, Amgen, Celgene, Lilly, Medac, Merck, Novartis, Pfizer, Roche, Sandoz, Sanofi Genzyme and UCB. JWJB has received grant/research support from Roche, and has been paid speaker for Roche and Lilly. RGD has been paid speaker for MSD, AbbVie, Novartis, Roche, Pfizer, Myllan and Sandoz. ED has received grant/research support from Independent Learning, Pfizer, combined funding for a research fellow from Celgene, Abbvie and Novartis, and has been paid instructor for Novartis to deliver training to nurses. LG has received grant/research support from Lilly, Pfizer and Sandoz, and has been consultant for AbbVie, Amgen, Biogen, BMS, Celgene, Janssen, Lilly, MSD, Novartis, Pfizer, Sandoz, Sanofi-Aventis and UCB Pharma. BJFvdB has been paid speaker for MSD, Abbvie and Biogen. MV has been paid speaker for Pfizer. AdT has received grants from Novartis, and has been paid speaker for Lilly and Pfizer. LC has received grant/research support through her institute from Novartis, Pfizer, MSD, Roche, Sanofi Aventis, AbbVie and Gebro Pharma.

Auteurs

Valentin Ritschl (V)

Section for Outcomes Research, Medical University of Vienna, Wien, Austria.
Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Wien, Austria.

Tanja A Stamm (TA)

Section for Outcomes Research, Medical University of Vienna, Wien, Austria tanja.stamm@meduniwien.ac.at.
Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Wien, Austria.

Daniel Aletaha (D)

Department of Rheumatology, Medical University of Vienna, Wien, Austria.

Johannes W J Bijlsma (JWJ)

Rheumatology, UMC Utrecht, Utrecht, The Netherlands.

Peter Böhm (P)

Deutsche Rheuma-Liga Bundesverband e.V, Bonn, Germany.

Razvan Gabriel Dragoi (RG)

Rehabilitation, Physical Medicine and Rheumatology, University of Medicine and Pharmacy Victor Babes Timisoara, Timisoara, Romania.

Emma Dures (E)

Department of Nursing and Midwifery, University of the West of England, Bristol, Bristol, UK.
Academic Rheumatology, Bristol Royal Infirmary, Bristol, UK.

Fernando Estévez-López (F)

Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

Laure Gossec (L)

Institut Pierre Louis d'Epidémiologie et de Santé Publique, INSERM, Sorbonne Universite, Paris, France.
APHP, Rheumatology Department, Hopital Universitaire Pitie Salpetriere, Paris, France.

Annamaria Iagnocco (A)

Scienze Cliniche e Biologiche, Università degli Studi di Torino, Torino, Italy.

Andrea Marques (A)

Rheumatology Department, Centro Hospitalar e Universitário de Coimbra, Health Sciences Research Unit: Nursing, Coimbra, Portugal.

Ellen Moholt (E)

Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.

Michal Nudel (M)

Mifrakim Tz'eirim, Haifa, Israel.

Bart J F van den Bemt (BJF)

Pharmacy, Sint Maartenskliniek, Nijmegen, The Netherlands.
Department of Pharmacy, Radboud Univiersity Medical Center, Nijmegen, The Netherlands.

Kirsten Viktil (K)

Hospital Pharmacy, Diakonhjemmet Hospital Pharmacy, Oslo, Norway.
School of Pharmacy, University of Oslo, Oslo, Norway.

Marieke Voshaar (M)

Department Psychology, Health and Technology, University of Twente, Enschede, The Netherlands.

Annette de Thurah (A)

Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Loreto Carmona (L)

Instituto de Salud Musculoesquelética (INMUSC), Madrid, Spain.

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