Levofloxacin induced bullous fixed drug eruption: a rare case report.
continuing
diabetes mellitus
drug misuse
drug-related side effects and adverse reactions
education
education department
hospital
pharmacy
Journal
European journal of hospital pharmacy : science and practice
ISSN: 2047-9956
Titre abrégé: Eur J Hosp Pharm
Pays: England
ID NLM: 101578294
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
20
10
2020
revised:
18
11
2020
accepted:
01
12
2020
pubmed:
24
12
2020
medline:
2
4
2022
entrez:
23
12
2020
Statut:
ppublish
Résumé
A 42-year-old male patient visited the outpatient department for follow-up with a history of respiratory tract infection and diabetes mellitus. His main symptom was peeling of his epidermal layer of skin, and bullous fixed drug eruption on the lower and upper limbs and bank region of the body. Following assessment, the patient was prescribed levothyroxine, hydroxychloroquine, levofloxacin, and a combination of sulfamethoxazole-trimethoprim. On assessing causality of the adverse drug reaction (ADR), different ADR assessment scales such as the WHO-UMC Scale, Naranjo Scale, and Hartwig's Severity Assessment Scale were used, and the ADR was found by these scales to be 'likely', 'moderate', and 'probable', respectively. It was found that ADRs such as bullous fixed drug eruptions are not fatal but can cause patient anxiety and a reduced quality of life. This case report will help physicians and clinicians to become aware and vigilant about the ADR caused by levofloxacin, facilitating its early detection and management.
Identifiants
pubmed: 33355292
pii: ejhpharm-2020-002566
doi: 10.1136/ejhpharm-2020-002566
pmc: PMC8899637
doi:
Substances chimiques
Levofloxacin
6GNT3Y5LMF
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e95-e96Informations de copyright
© European Association of Hospital Pharmacists 2022. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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