Cytochromes P450: terpene detoxification and pheromone production in bark beetles.
Journal
Current opinion in insect science
ISSN: 2214-5753
Titre abrégé: Curr Opin Insect Sci
Pays: Netherlands
ID NLM: 101635599
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
02
06
2020
revised:
11
11
2020
accepted:
24
11
2020
pubmed:
29
12
2020
medline:
11
8
2021
entrez:
28
12
2020
Statut:
ppublish
Résumé
Bark beetles (family: Curculionidae; subfamily: Scolytinae) in the Dendroctonus and Ips genera are the most destructive forest pests in the Northern hemisphere. They use cytochromes P450 (P450s) to detoxify tree-produced terpenes to produce pheromones, in de novo pheromone production and to oxidize odorants on antennae. Many Dendroctonus spp. use trans-verbenol as an aggregation pheromone, and it is formed from host-tree produced α-pinene hydroxylated by CYP6DE1 during larval stages, stored as verbenyl ester of fatty acids, and then released when the female begins feeding on a new host tree. Ips spp. hydroxylate de novo produced myrcene to form ipsdienol. Subsequent steps form the appropriate enantiomeric composition of ipsdienol and convert ipsdienol to ipsenol. In this article we review recent progress in elucidating the functions of P450s in Ips and Dendroctonus species and in doing so provide insights into the role of these enzymes in host phytochemical detoxification and pheromone production.
Identifiants
pubmed: 33359166
pii: S2214-5745(20)30154-1
doi: 10.1016/j.cois.2020.11.010
pii:
doi:
Substances chimiques
Alcohols
0
Bicyclic Monoterpenes
0
Pheromones
0
Terpenes
0
ipsenol
02H2YW09TH
Cytochrome P-450 Enzyme System
9035-51-2
verbenol
G0F32F922S
alpha-pinene
JPF3YI7O34
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
97-102Informations de copyright
Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.