A review found inadequate reporting of case-control studies of risk factors for pancreatic cancer.


Journal

Journal of clinical epidemiology
ISSN: 1878-5921
Titre abrégé: J Clin Epidemiol
Pays: United States
ID NLM: 8801383

Informations de publication

Date de publication:
05 2021
Historique:
received: 02 07 2020
revised: 08 12 2020
accepted: 15 12 2020
pubmed: 29 12 2020
medline: 28 9 2021
entrez: 28 12 2020
Statut: ppublish

Résumé

Case-control studies are often used to identify the risk factors for pancreatic cancer. The objective of this study was to evaluate the reporting of case-control studies of the risk factors for pancreatic cancer using the Strengthening The Reporting of OBservational Studies in Epidemiology (STROBE) for case-control studies checklist. We conducted a comprehensive literature search of the MEDLINE and EMBASE databases to identify reports of case-control studies published between 2016 and 2018. We scored article reporting using a reporting adherence form developed from the STROBE checklist for case-control studies, consisting of 14 STROBE items related to the title, abstract, methods, and results sections. We included reports of 47 case-control studies investigating a variety of risk factors, such as medical conditions and lifestyle factors. Reporting was inconsistent and inadequate. Efforts to address bias and how the study size was arrived at were particularly poorly described. Study cases were described in more detail than study controls. Reporting of case-control studies remains inadequate more than 10 years after the STROBE reporting guideline was published. Our findings suggest that authors do not understand the extent to which study methods and findings should be reported to enable studies to be fully understood, and their methods reproduced.

Identifiants

pubmed: 33359318
pii: S0895-4356(20)31224-5
doi: 10.1016/j.jclinepi.2020.12.020
pmc: PMC8168827
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

32-42

Subventions

Organisme : Cancer Research UK
ID : C49297/A27294
Pays : United Kingdom
Organisme : Department of Health
Pays : United Kingdom

Informations de copyright

Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.

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Auteurs

Angela MacCarthy (A)

Centre for Statistics in Medicine, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7LD, UK. Electronic address: angela.maccarthy@csm.ox.ac.uk.

Paula Dhiman (P)

Centre for Statistics in Medicine, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7LD, UK; NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.

Shona Kirtley (S)

Centre for Statistics in Medicine, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7LD, UK.

Patricia Logullo (P)

Centre for Statistics in Medicine, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7LD, UK; NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.

Bethan Copsey (B)

Centre for Statistics in Medicine, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7LD, UK.

Gary S Collins (GS)

Centre for Statistics in Medicine, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7LD, UK; NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.

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