The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.
Binding Sites
Chromatin
/ genetics
Chromatin Assembly and Disassembly
DNA-Binding Proteins
/ chemistry
Epigenesis, Genetic
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Histones
/ metabolism
Humans
Multiprotein Complexes
/ metabolism
Organoids
Protein Binding
Protein Transport
Sarcoma, Synovial
/ genetics
Transcriptome
Journal
Life science alliance
ISSN: 2575-1077
Titre abrégé: Life Sci Alliance
Pays: United States
ID NLM: 101728869
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
05
06
2020
revised:
01
12
2020
accepted:
10
12
2020
entrez:
28
12
2020
pubmed:
29
12
2020
medline:
14
9
2021
Statut:
epublish
Résumé
Synovial sarcoma (SyS) is an aggressive mesenchymal malignancy invariably associated with the chromosomal translocation t(X:18; p11:q11), which results in the in-frame fusion of the BAF complex gene
Identifiants
pubmed: 33361335
pii: 4/2/e202000808
doi: 10.26508/lsa.202000808
pmc: PMC7768195
pii:
doi:
Substances chimiques
BANF1 protein, human
0
Chromatin
0
DNA-Binding Proteins
0
Histones
0
Multiprotein Complexes
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2020 Boulay et al.
Références
Elife. 2018 Nov 15;7:
pubmed: 30431433
Nat Biotechnol. 2010 May;28(5):511-5
pubmed: 20436464
Cancer Cell. 2018 Mar 12;33(3):527-541.e8
pubmed: 29502955
Nat Genet. 2017 Feb;49(2):282-288
pubmed: 27941795
Genome Biol. 2014;15(12):550
pubmed: 25516281
PLoS One. 2009 Nov 19;4(11):e7904
pubmed: 19936258
Nature. 2007 Aug 2;448(7153):553-60
pubmed: 17603471
Cell. 2017 Nov 2;171(4):950-965.e28
pubmed: 29100075
Nature. 2012 Sep 6;489(7414):57-74
pubmed: 22955616
Genome Biol. 2008;9(9):R137
pubmed: 18798982
Nat Rev Cancer. 2018 Jul;18(7):407-418
pubmed: 29692415
Cancer Res. 2014 Nov 15;74(22):6610-22
pubmed: 25261238
Cells. 2020 Jan 16;9(1):
pubmed: 31963307
Science. 2019 Jun 07;364(6444):952-955
pubmed: 31171691
Cancer Cell. 2007 Apr;11(4):375-88
pubmed: 17418413
Bioinformatics. 2009 Jul 15;25(14):1754-60
pubmed: 19451168
Cancer Cell. 2012 Jun 12;21(6):807-21
pubmed: 22698405
PLoS Comput Biol. 2013;9(8):e1003118
pubmed: 23950696
Bioinformatics. 2014 Apr 1;30(7):923-30
pubmed: 24227677
Nat Cell Biol. 2018 Dec;20(12):1410-1420
pubmed: 30397315
Cancer Discov. 2015 Feb;5(2):124-34
pubmed: 25614489
Sci Rep. 2016 Feb 24;6:22113
pubmed: 26905812
EMBO J. 1996 Oct 1;15(19):5370-82
pubmed: 8895581
Nat Genet. 2017 Feb;49(2):213-222
pubmed: 27941796
Front Oncol. 2019 Oct 18;9:1078
pubmed: 31681608
J Biol Chem. 2017 Feb 17;292(7):2893-2902
pubmed: 28073915
Cell Rep. 2016 Jan 12;14(2):332-46
pubmed: 26748712
Cancer Res. 2008 Apr 1;68(7):2176-85
pubmed: 18381423
Swiss Med Wkly. 2018 Dec 02;148:w14667
pubmed: 30506527
Genes Dev. 2019 Jan 1;33(1-2):4-5
pubmed: 30602437
Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3843-8
pubmed: 11274403
Bioinformatics. 2014 Jun 1;30(11):1618-9
pubmed: 24489365
Genes Dev. 2019 Jan 1;33(1-2):55-60
pubmed: 30567998
Bioessays. 2016 Sep;38(9):863-8
pubmed: 27374980
Annu Rev Pathol. 2020 Jan 24;15:211-234
pubmed: 31550983
Exp Hematol. 2017 Apr;48:12-31
pubmed: 28087428
Cancer Res. 2009 Mar 1;69(5):1776-81
pubmed: 19208848
Oncogene. 2012 May 3;31(18):2323-34
pubmed: 21996728
Cell Biochem Biophys. 2011 Jun;60(1-2):61-8
pubmed: 21468693
Bioinformatics. 2013 Jan 1;29(1):15-21
pubmed: 23104886
Hum Mol Genet. 1999 Apr;8(4):585-91
pubmed: 10072425
Cell. 2013 Mar 28;153(1):71-85
pubmed: 23540691
Bioinformatics. 2010 Mar 15;26(6):841-2
pubmed: 20110278
Cancer Cell. 2018 Jun 11;33(6):1128-1141.e7
pubmed: 29861296
Cancer Cell. 2012 Mar 20;21(3):333-47
pubmed: 22439931
Brief Bioinform. 2013 Mar;14(2):178-92
pubmed: 22517427
Cancer Cell. 2018 Aug 13;34(2):346-348
pubmed: 30107180
Cancer Res. 2007 Jan 1;67(1):398-407
pubmed: 17210723
Genes Dev. 1996 Sep 1;10(17):2117-30
pubmed: 8804307