Perspectives on skin disorder diagnosis among people living with HIV in southeastern Romania.
HIV status
dermoscopy
diagnosis
immunodeficiency
skin disorders
Journal
Experimental and therapeutic medicine
ISSN: 1792-0981
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
21
09
2020
accepted:
21
10
2020
entrez:
28
12
2020
pubmed:
29
12
2020
medline:
29
12
2020
Statut:
ppublish
Résumé
The beginnings of the human immunodeficiency virus (HIV) pandemic are closely linked to dermatological conditions. A large part of the population living with HIV (PLWH) has a series of skin conditions that determine at some point, a visit to the dermatologist. The introduction of highly active antiretroviral therapy (HAART) more than 20 years ago has diminished the range of dermatological conditions, with improved immunosuppression of CD4 lymphocytes. The study aimed to describe the prevalence of the diagnosed type of skin changes in PLWH receiving antiretroviral therapy and their stratification according to the degree of immunodeficiency. A prospective study was conducted on 57 PLWH evaluated monthly at an HIV outpatient clinic, from a tertiary hospital in southeastern Romania. Clinical examination and dermoscopy revealed the existence of a wide range of dermatological conditions; all 57 patients (100%) being diagnosed with one or more dermatological conditions. As our study shows, the prevalence of different dermatoses among PLWH varies depending on the geographical region. At the same time, under HAART, the image of dermatoses associated with decreased immunity from HIV infection has changed. The skin changes of PLWH no longer fully follow the classical staging, based on the degree of immunosuppression.
Identifiants
pubmed: 33363608
doi: 10.3892/etm.2020.9529
pii: ETM-0-0-09529
pmc: PMC7725011
doi:
Types de publication
Journal Article
Langues
eng
Pagination
97Informations de copyright
Copyright © 2020, Spandidos Publications.
Références
Int J Dermatol. 2019 Oct;58(10):1165-1171
pubmed: 30927252
MMWR Recomm Rep. 1992 Dec 18;41(RR-17):1-19
pubmed: 1361652
Cold Spring Harb Perspect Med. 2014 Dec 01;4(12):a015339
pubmed: 25452424
J Invest Dermatol. 2006 Jul;126(7):1490-6
pubmed: 16645597
J Eur Acad Dermatol Venereol. 2019 Jan;33(1):e46-e47
pubmed: 29959784
Exp Ther Med. 2020 Oct;20(4):3421-3424
pubmed: 32905089
Rom J Morphol Embryol. 2017;58(3):1009-1015
pubmed: 29250682
J Int AIDS Soc. 2011 Jan 24;14:5
pubmed: 21261982
PLoS One. 2014 Jun 09;9(6):e99533
pubmed: 24911008
F1000Res. 2019 Jun 28;8:
pubmed: 31297183
J Am Acad Dermatol. 1985 Dec;13(6):947-51
pubmed: 2934444
Emerg Med Clin North Am. 2010 May;28(2):355-68, Table of Contents
pubmed: 20413018
AIDS. 2012 Jun 19;26(10):1231-41
pubmed: 22706009
Exp Ther Med. 2020 Jul;20(1):91-96
pubmed: 32518604
An Bras Dermatol. 2017 May-Jun;92(3):423-425
pubmed: 29186267
Oncol Lett. 2016 Sep;12(3):1779-1782
pubmed: 27602111
Dermatology. 2019;235(6):495-500
pubmed: 31586992
J Glob Infect Dis. 2018 Apr-Jun;10(2):80-83
pubmed: 29910568
Br J Dermatol. 2018 May;178(5):1111-1118
pubmed: 29247509