Seroprevalence Study on West Nile Virus (WNV) Infection, a Hidden Viral Disease in Fars Province, Southern Iran.
Iran
Seroprevalence
West Nile virus
Journal
Journal of arthropod-borne diseases
ISSN: 2322-1984
Titre abrégé: J Arthropod Borne Dis
Pays: Iran
ID NLM: 101593448
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
12
09
2019
accepted:
10
12
2019
entrez:
28
12
2020
pubmed:
29
12
2020
medline:
29
12
2020
Statut:
epublish
Résumé
West Nile Virus, a mosquito-borne flavivirus, causes a variety of symptoms in human, from asymptomatic infection to neuroinvasive disease. Several studies have been conducted on the seroprevalence of WNV infection in different areas from Iran. This study was performed to find the presence of antiviral antibodies in human serum among some high risk population and awareness of health care staff about symptom of the WNV infection. Study performed in five geographical districts based on high population of immigrant and domestic birds and prevalence of the antiviral antibodies in horses which was reported previously. Totally 150 human blood samples were collected during 2018. The samples collected from patients referred to the clinics. The ELISA method used to detect IgG and IgM antibody against WNV. Logistic regression models used to analyze the effect of sex, age, keeping birds and urban/rural residence on the risk of infection. The awareness of health care staff about symptom of infection surveyed. From all blood donors, 41 samples (27.33%) showed positive to IgG antibody. From which 56.10% were males and remaining females. None of the mentioned factors had a significant relationship. Health care staff had less attention to the infection. Although the prevalence of antibodies was relatively high, due to the similarity to other viral diseases, health care staff had less attention to the disease. The study showed that people in these areas have been exposed to the virus. Further research activities are recommended for control of this arbovirus.
Sections du résumé
BACKGROUND
BACKGROUND
West Nile Virus, a mosquito-borne flavivirus, causes a variety of symptoms in human, from asymptomatic infection to neuroinvasive disease. Several studies have been conducted on the seroprevalence of WNV infection in different areas from Iran. This study was performed to find the presence of antiviral antibodies in human serum among some high risk population and awareness of health care staff about symptom of the WNV infection.
METHODS
METHODS
Study performed in five geographical districts based on high population of immigrant and domestic birds and prevalence of the antiviral antibodies in horses which was reported previously. Totally 150 human blood samples were collected during 2018. The samples collected from patients referred to the clinics. The ELISA method used to detect IgG and IgM antibody against WNV. Logistic regression models used to analyze the effect of sex, age, keeping birds and urban/rural residence on the risk of infection. The awareness of health care staff about symptom of infection surveyed.
RESULTS
RESULTS
From all blood donors, 41 samples (27.33%) showed positive to IgG antibody. From which 56.10% were males and remaining females. None of the mentioned factors had a significant relationship. Health care staff had less attention to the infection.
CONCLUSION
CONCLUSIONS
Although the prevalence of antibodies was relatively high, due to the similarity to other viral diseases, health care staff had less attention to the disease. The study showed that people in these areas have been exposed to the virus. Further research activities are recommended for control of this arbovirus.
Identifiants
pubmed: 33365345
doi: 10.18502/jad.v14i2.3735
pii: jad-14-173
pmc: PMC7738928
doi:
Types de publication
Journal Article
Langues
eng
Pagination
173-184Informations de copyright
Copyright© Iranian Society of Medical Entomology & Tehran University of Medical Sciences.
Références
J Clin Virol. 2013 Oct;58(2):351-3
pubmed: 23562617
J Clin Microbiol. 2000 Jun;38(6):2232-9
pubmed: 10834982
Antiviral Res. 2013 Jul;99(1):1-5
pubmed: 23624155
J Arthropod Borne Dis. 2016 Jan 06;10(3):315-27
pubmed: 27308290
Vector Borne Zoonotic Dis. 2019 Jan;19(1):45-50
pubmed: 29985780
Transbound Emerg Dis. 2019 Mar;66(2):617-621
pubmed: 30506625
J Med Entomol. 2008 Jan;45(1):125-8
pubmed: 18283952
Acta Trop. 2018 Jun;182:64-68
pubmed: 29474832
Transbound Emerg Dis. 2016 Dec;63(6):e153-e159
pubmed: 25753775
Int J Environ Res Public Health. 2018 Feb 23;15(2):
pubmed: 29473903
Ann Ist Super Sanita. 2016 Apr-Jun;52(2):198-204
pubmed: 27364394
Am Fam Physician. 2003 Aug 15;68(4):653-60
pubmed: 12952382
Clin Med Res. 2003 Jan;1(1):5-12
pubmed: 15931279
J Am Mosq Control Assoc. 2015 Mar;31(1):1-6
pubmed: 25843170
Trop Geogr Med. 1970 Jun;22(2):183-8
pubmed: 4317129
Asian Pac J Trop Med. 2015 Mar;8(3):203-5
pubmed: 25902161
Clin Microbiol Rev. 2012 Oct;25(4):635-48
pubmed: 23034323
Vector Borne Zoonotic Dis. 2015 Dec;15(12):750-4
pubmed: 26565610
Vector Borne Zoonotic Dis. 2011 Oct;11(10):1377-81
pubmed: 21923253
Epidemiol Infect. 2012 Aug;140(8):1525-9
pubmed: 22008154
Rev Sci Tech. 2012 Dec;31(3):829-44
pubmed: 23520737
J Clin Microbiol. 2005 Sep;43(9):4316-20
pubmed: 16145071
Indian J Hematol Blood Transfus. 2016 Sep;32(3):343-6
pubmed: 27429528
J Clin Microbiol. 2004 Feb;42(2):727-33
pubmed: 14766844
Hippokratia. 2015 Jan-Mar;19(1):34-6
pubmed: 26435644
Arch Iran Med. 2010 Jan;13(1):1-4
pubmed: 20039761
PLoS One. 2019 Jun 3;14(6):e0217854
pubmed: 31158250
Epidemiol Infect. 2011 Oct;139(10):1587-93
pubmed: 21396143
J Arthropod Borne Dis. 2019 Jun 24;13(2):224-233
pubmed: 31803784
Sci Rep. 2018 Feb 8;8(1):2599
pubmed: 29422507
Vector Borne Zoonotic Dis. 2013 Aug;13(8):586-9
pubmed: 23697768
Acta Trop. 2016 Nov;163:26-31
pubmed: 27469618
J Clin Virol. 2014 Sep;61(1):152-5
pubmed: 24985196
Emerg Infect Dis. 2005 Nov;11(11):1774-7
pubmed: 16318737
Parasit Vectors. 2017 Mar 27;10(1):163
pubmed: 28347323
Emerg Infect Dis. 2004 Oct;10(10):1885-6
pubmed: 15515250
Am J Trop Med Hyg. 2012 May;86(5):884-94
pubmed: 22556092
PLoS Negl Trop Dis. 2019 Jan 29;13(1):e0007081
pubmed: 30695031