Prevalence of Myocardial Infarction in Patients With Chronic Pancreatitis.
Adolescent
Adult
Age Factors
Aged
Comorbidity
Databases, Factual
Female
Humans
Life Style
Male
Middle Aged
Myocardial Infarction
/ diagnosis
Pancreatitis, Chronic
/ diagnosis
Prevalence
Race Factors
Retrospective Studies
Risk Assessment
Risk Factors
Sex Factors
Time Factors
United States
/ epidemiology
Young Adult
Journal
Pancreas
ISSN: 1536-4828
Titre abrégé: Pancreas
Pays: United States
ID NLM: 8608542
Informations de publication
Date de publication:
01 01 2021
01 01 2021
Historique:
entrez:
28
12
2020
pubmed:
29
12
2020
medline:
15
12
2021
Statut:
ppublish
Résumé
We conducted this study to ascertain whether chronic inflammation secondary to chronic pancreatitis (CP) has any association with myocardial infarction(MI). Data were collected from a commercial database (Explorys, Inc, IBM Watson, Ohio). Adults with the diagnosis of "chronic pancreatitis," based on Systematized Nomenclature of Medicine-Clinical Terms, were included in the CP group, and the rest of the patients were included in the non-CP group. The prevalence of MI was compared in both groups, and statistical multivariate model was performed. A total of 28,842,210 patients were included in the study. The overall prevalence of MI was 14.22% in the CP group as compared with 3.23% in the non-CP group (P < 0.0001). In the multivariate analysis, the odds ratio (OR) for MI in CP group was 1.453 (95% confidence interval, 1.418-1.488, P < 0.0001). Hypertension was a strong predictor for MI in the CP group with an OR of 3.2 (95% confidence interval, 3.0-3.5), followed by chronic kidney disease, older than 65 years, dyslipidemia, diabetes mellitus, obesity, alcohol abuse, smoking, White race, and male sex. This study showed that CP is associated with comorbidities, which can increase the prevalence and OR of MI.
Identifiants
pubmed: 33370030
doi: 10.1097/MPA.0000000000001721
pii: 00006676-202101000-00015
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
99-103Informations de copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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