A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications.

bioactive glass bioactivity mesoporous nanomaterials porosity scaffold sol–gel tissue engineering

Journal

Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216

Informations de publication

Date de publication:
21 Dec 2020
Historique:
received: 19 11 2020
revised: 12 12 2020
accepted: 16 12 2020
entrez: 29 12 2020
pubmed: 30 12 2020
medline: 30 12 2020
Statut: epublish

Résumé

Bioactive glasses (BGs) are traditionally known to be able to bond to living bone and stimulate bone regeneration. The production of such materials in a mesoporous form allowed scientists to dramatically expand the versatility of oxide-based glass systems as well as their applications in biomedicine. These nanostructured materials, called mesoporous bioactive glasses (MBGs), not only exhibit an ultrafast mineralization rate but can be used as vehicles for the sustained delivery of drugs, which are hosted inside the mesopores, and therapeutic ions, which are released during material dissolution in contact with biological fluids. This review paper summarizes the main strategies for the preparation of MBGs, as well as their properties and applications in the biomedical field, with an emphasis on the methodological aspects and the promise of hierarchical systems with multiscale porosity.

Identifiants

pubmed: 33371415
pii: nano10122571
doi: 10.3390/nano10122571
pmc: PMC7767440
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Carla Migneco (C)

Department of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, Italy.

Elisa Fiume (E)

Department of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, Italy.
Department of Mechanical and Aerospace Engineering (DIMEAS), Politecnico di Torino, 10129 Torino, Italy.

Enrica Verné (E)

Department of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, Italy.

Francesco Baino (F)

Department of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, Italy.

Classifications MeSH