Prevalence and predictors of suicidality and non-suicidal self-harm among individuals at clinical high-risk for psychosis: Results from a community-recruited sample.


Journal

Early intervention in psychiatry
ISSN: 1751-7893
Titre abrégé: Early Interv Psychiatry
Pays: Australia
ID NLM: 101320027

Informations de publication

Date de publication:
10 2021
Historique:
revised: 03 09 2020
received: 08 07 2020
accepted: 15 11 2020
pubmed: 30 12 2020
medline: 29 10 2021
entrez: 29 12 2020
Statut: ppublish

Résumé

Suicidal thoughts and behaviours are prevalent in individuals with schizophrenia. However, research examining the prevalence and predictors of suicidality and self-harm in participants at clinical high-risk for psychosis (CHR-P) is limited and mostly focuses on help-seeking participants recruited through clinical pathways. The current study sought to assess the prevalence of suicidality and self-harm and identify predictors of current suicidal ideation in community-recruited CHR-P participants. Data were available for 130 CHR-P participants, 15 participants with first-episode psychosis (FEP), 47 participants not fulfilling CHR-P criteria (CHR-Ns) and 53 healthy controls. Current and lifetime suicidality and self-harm were assessed using the Mini-International Neuropsychiatric Interview and the Comprehensive Assessment of At-Risk Mental States (CAARMS). Multivariable logistic regression analysis was used to determine predictors of current suicidal ideation in the CHR-P group. A considerable proportion of CHR-P participants disclosed current suicidal ideation (34.6%). Overall, FEP individuals were at greatest risk, with considerably high prevalence rates for current suicidal ideation (73.3%), lifetime self-harm behaviour (60.0%) and lifetime suicide attempt (60.0%). In the CHR-P sample, current suicidal ideation was predicted by lifetime suicide attempts, lower CAARMS severity, impaired social functioning and greater comorbidity. Our findings suggest that suicidality and self-harm are highly prevalent in community-recruited CHR-P and FEP individuals. Accordingly, these results highlight the importance of further research into the determinants of suicidality and self-harm during at-risk and early stages of psychosis, and the implementation of intervention strategies to reduce adverse outcomes in these populations.

Identifiants

pubmed: 33372364
doi: 10.1111/eip.13075
pmc: PMC8451831
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1256-1265

Subventions

Organisme : Medical Research Council
ID : MR/N003403/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/L011689/1
Pays : United Kingdom

Informations de copyright

© 2020 The Authors. Early Intervention in Psychiatry Published by John Wiley & Sons Australia, Ltd.

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Auteurs

Kate Haining (K)

Institute of Neuroscience and Psychology, University of Glasgow, Scotland, UK.

Olga Karagiorgou (O)

Institute of Neuroscience and Psychology, University of Glasgow, Scotland, UK.

Ruchika Gajwani (R)

Institute of Health and Wellbeing, University of Glasgow, Scotland, UK.

Joachim Gross (J)

Institute of Neuroscience and Psychology, University of Glasgow, Scotland, UK.

Andrew I Gumley (AI)

Institute of Health and Wellbeing, University of Glasgow, Scotland, UK.

Stephen M Lawrie (SM)

Department of Psychiatry, University of Edinburgh, Edinburgh, Scotland, UK.

Matthias Schwannauer (M)

Department of Clinical Psychology, University of Edinburgh, Edinburgh, Scotland, UK.

Frauke Schultze-Lutter (F)

Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Department of Psychology and Mental Health, Faculty of Psychology, Airlangga University, Surabaya, Indonesia.
University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

Peter J Uhlhaas (PJ)

Institute of Neuroscience and Psychology, University of Glasgow, Scotland, UK.
Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.

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