Quantitative profiling of glycerides, glycerophosphatides and sphingolipids in Chinese human milk with ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry.
Human milk
OPL
Polar lipids (PLs)
Sphingolipids
UPLC/Q-TOF-MS
Journal
Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639
Informations de publication
Date de publication:
01 Jun 2021
01 Jun 2021
Historique:
received:
02
09
2020
revised:
01
12
2020
accepted:
07
12
2020
pubmed:
30
12
2020
medline:
9
3
2021
entrez:
29
12
2020
Statut:
ppublish
Résumé
Human milk lipids are an important energy source and essential nutrients for the growth and development of infants. The UPLC/Q-TOF-MS was used to qualitatively and quantitatively analyze human milk lipids. Totally, 411 species of lipids were identified, in which the content of OPL was generally higher than that of OPO; SM (75.38 mg/L, 40.39%), PE (51.12 mg/L, 27.39%) and PC (40.10 mg/L, 21.49%) had the highest contents among polar lipids, mainly including SM42:2:2 (22.24 mg/L), PE36:2 (C18:0-C18:2, 21.39 mg/L) and PC36:2 (C18:0-C18:2, 19.80 mg/L). In human milk, TAG56:7 (137.14 mg/L), TAG56:8 (59.49 mg/L), TAG58:8 (65.90 mg/L) and TAG58:9 (49.99 mg/L) were the main sources of AA and DHA; PE was an important source of AA and DHA in polar lipids; and linoleic acyl in glycerides and phospholipids had higher contents than other polyunsaturated fatty acyls. These results provided the scientific basis for the simulation of human milk at molecular level.
Identifiants
pubmed: 33373822
pii: S0308-8146(20)32719-9
doi: 10.1016/j.foodchem.2020.128857
pii:
doi:
Substances chimiques
Glycerides
0
Phospholipids
0
Sphingolipids
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
128857Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.