Antimicrobial Resistance in Pathogens Isolated from Blood Cultures: A Two-Year Multicenter Hospital Surveillance Study in Italy.

Italy Multi-Drug Resistance antimicrobial resistance bloodstream infection hospital surveillance

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
24 Dec 2020
Historique:
received: 02 12 2020
revised: 21 12 2020
accepted: 22 12 2020
entrez: 30 12 2020
pubmed: 31 12 2020
medline: 31 12 2020
Statut: epublish

Résumé

Antimicrobial resistance (AMR) is one of the most concerning issues in medicine today. The objectives of this study were to investigate the AMR distribution of the blood-borne pathogens isolated over a two-year period in an Italian region. A retrospective electronic record review of laboratory-confirmed bloodstream infections (BSIs) was done, and data from three major diagnostic laboratories were used. Twelve invasive clinically important bacteria species were included in the sample. During the study period, 1228 positive BSIs were collected. The most common pathogens were The results display an alarming prevalence of AMR among hospital isolated pathogens, consistently higher than the European average. Information from surveillance systems to better characterize the trend in the incidence of AMR at local and national levels is needed.

Sections du résumé

BACKGROUND BACKGROUND
Antimicrobial resistance (AMR) is one of the most concerning issues in medicine today. The objectives of this study were to investigate the AMR distribution of the blood-borne pathogens isolated over a two-year period in an Italian region.
METHODS METHODS
A retrospective electronic record review of laboratory-confirmed bloodstream infections (BSIs) was done, and data from three major diagnostic laboratories were used. Twelve invasive clinically important bacteria species were included in the sample.
RESULTS RESULTS
During the study period, 1228 positive BSIs were collected. The most common pathogens were
CONCLUSION CONCLUSIONS
The results display an alarming prevalence of AMR among hospital isolated pathogens, consistently higher than the European average. Information from surveillance systems to better characterize the trend in the incidence of AMR at local and national levels is needed.

Identifiants

pubmed: 33374232
pii: antibiotics10010010
doi: 10.3390/antibiotics10010010
pmc: PMC7824585
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

PLoS Med. 2011 Oct;8(10):e1001104
pubmed: 22022233
JAC Antimicrob Resist. 2019 Dec;1(3):dlz070
pubmed: 32280945
Crit Care. 2016 Jun 22;20(1):136
pubmed: 27329228
Antimicrob Resist Infect Control. 2018 Apr 3;7:48
pubmed: 29636910
Antibiotics (Basel). 2020 Oct 18;9(10):
pubmed: 33081002
Antibiotics (Basel). 2020 Feb 23;9(2):
pubmed: 32102195
Lancet Infect Dis. 2019 Jan;19(1):56-66
pubmed: 30409683
Health Commun. 2015;30(3):309-14
pubmed: 25121990
Infect Control Hosp Epidemiol. 2017 Jul;38(7):823-831
pubmed: 28580893
Antimicrob Resist Infect Control. 2018 Aug 9;7:98
pubmed: 30116525
Euro Surveill. 2016 Aug 18;21(33):
pubmed: 27562950
Euro Surveill. 2015;20(45):
pubmed: 26675038
Clin Infect Dis. 1999 Aug;29(2):239-44
pubmed: 10476719
Clin Infect Dis. 1997 Jun;24(6):1068-78
pubmed: 9195059
Antibiotics (Basel). 2020 Nov 28;9(12):
pubmed: 33260698
J Antimicrob Chemother. 2012 Apr;67(4):802-9
pubmed: 22223229
Bull World Health Organ. 2004 Dec;82(12):928-34
pubmed: 15654407
Clin Infect Dis. 2004 Aug 1;39(3):309-17
pubmed: 15306996
Antimicrob Resist Infect Control. 2017 Jun 13;6:64
pubmed: 28630688

Auteurs

Francesca Licata (F)

Department of Health Sciences, School of Medicine, University of Catanzaro "Magna Græcia", Viale Europa, Germaneto, 88100 Catanzaro, Italy.

Angela Quirino (A)

Department of Health Sciences, School of Medicine, University of Catanzaro "Magna Græcia", Viale Europa, Germaneto, 88100 Catanzaro, Italy.

Davide Pepe (D)

Department of Health Sciences, School of Medicine, University of Catanzaro "Magna Græcia", Viale Europa, Germaneto, 88100 Catanzaro, Italy.

Giovanni Matera (G)

Department of Health Sciences, School of Medicine, University of Catanzaro "Magna Græcia", Viale Europa, Germaneto, 88100 Catanzaro, Italy.

Aida Bianco (A)

Department of Health Sciences, School of Medicine, University of Catanzaro "Magna Græcia", Viale Europa, Germaneto, 88100 Catanzaro, Italy.
Department of Health Sciences, School of Medicine, University of Catanzaro "Magna Græcia", Viale Europa, Germaneto, 88100 Catanzaro, Italy.

Classifications MeSH