Postoperative Delirium is a Risk Factor of Poor Evolution Three Years After Cardiac Surgery: An Observational Cohort Study.
Activities of Daily Living
Aged
Cardiopulmonary Bypass
/ adverse effects
Cognition
/ physiology
Cohort Studies
Diabetes Mellitus
Emergence Delirium
/ epidemiology
Female
Functional Status
Humans
Logistic Models
Male
Mental Status and Dementia Tests
Middle Aged
Quality of Life
Risk Factors
Sex Factors
cardiac surgery
delirium
dependence
mortality
quality of life
Journal
Clinical interventions in aging
ISSN: 1178-1998
Titre abrégé: Clin Interv Aging
Pays: New Zealand
ID NLM: 101273480
Informations de publication
Date de publication:
2020
2020
Historique:
received:
10
07
2020
accepted:
04
09
2020
entrez:
30
12
2020
pubmed:
31
12
2020
medline:
22
4
2021
Statut:
epublish
Résumé
After cardiac surgery, postoperative delirium (POD) is common and is associated with long-term changes in cognitive function. Impact on health-related quality of life (QOL) and long-term dependence are not well known. This aim of this study is to evaluate the role of POD in poor evolution at three years after surgery including poor QOL and dependence and mortality. We enrolled and followed 173 patients 60 years of age or older who were planning to undergo cardiac surgery with cardiopulmonary bypass. The primary composite outcome was death of any causes, or patients with either a loss of QOL (evaluated with of EuroQuol verbal 5D EQ5D less than 50), or a loss of two points on the instrumental activities of daily living occurring three years after surgery. POD was diagnosed with the use of Confusion Assessment Method. Multivariate logistic regression was performed. At three years, 74 patients (42.8%) had a poor evolution. Independent risk factors in poor patient evolution were sex (female gender; OR: 3.6; 95%CI: 1.45-8.7; After cardiac surgery, POD significantly altered patient evolution and increased risk of dependence and loss of QOL.
Sections du résumé
BACKGROUND
BACKGROUND
After cardiac surgery, postoperative delirium (POD) is common and is associated with long-term changes in cognitive function. Impact on health-related quality of life (QOL) and long-term dependence are not well known. This aim of this study is to evaluate the role of POD in poor evolution at three years after surgery including poor QOL and dependence and mortality.
PATIENTS AND METHODS
METHODS
We enrolled and followed 173 patients 60 years of age or older who were planning to undergo cardiac surgery with cardiopulmonary bypass. The primary composite outcome was death of any causes, or patients with either a loss of QOL (evaluated with of EuroQuol verbal 5D EQ5D less than 50), or a loss of two points on the instrumental activities of daily living occurring three years after surgery. POD was diagnosed with the use of Confusion Assessment Method. Multivariate logistic regression was performed.
RESULTS
RESULTS
At three years, 74 patients (42.8%) had a poor evolution. Independent risk factors in poor patient evolution were sex (female gender; OR: 3.6; 95%CI: 1.45-8.7;
CONCLUSION
CONCLUSIONS
After cardiac surgery, POD significantly altered patient evolution and increased risk of dependence and loss of QOL.
Identifiants
pubmed: 33376313
doi: 10.2147/CIA.S265797
pii: 265797
pmc: PMC7755370
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2375-2381Informations de copyright
© 2020 Labaste et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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