Role of lncRNA PART1 in intervertebral disc degeneration and associated underlying mechanism.
intervertebral disc degeneration
long non-coding RNA prostate androgen-regulated transcript 1
microRNA-190a-3p
Journal
Experimental and therapeutic medicine
ISSN: 1792-0981
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
06
05
2020
accepted:
08
10
2020
entrez:
30
12
2020
pubmed:
31
12
2020
medline:
31
12
2020
Statut:
ppublish
Résumé
Intervertebral disc degeneration (IDD) is a chronic skeletal muscle degeneration disease. Previous studies have demonstrated that long non-coding RNAs (lncRNAs) exert significant roles in serious illnesses. Prostate androgen-regulated transcript 1 (PART1) is an identified lncRNA that has been reported to be a regulator in a number of diseases. However, the potential effects of PART1 in IDD have yet to be fully elucidated. The present study aimed to investigate the roles of lncRNA PART1 in IDD and identify a possible underlying mechanism. Human nucleus pulposus (NP) cells were first exposed to lipopolysaccharide (LPS) to construct
Identifiants
pubmed: 33376513
doi: 10.3892/etm.2020.9563
pii: ETM-0-0-09563
pmc: PMC7751492
doi:
Types de publication
Journal Article
Langues
eng
Pagination
131Informations de copyright
Copyright: © Zhang et al.
Références
Spine (Phila Pa 1976). 2019 Aug 1;44(15):E873-E881
pubmed: 30817728
Behav Brain Res. 2017 Sep 29;335:80-87
pubmed: 28647595
J Pineal Res. 2017 Oct;63(3):
pubmed: 28719035
Trop Anim Health Prod. 2020 Jul;52(4):1561-1572
pubmed: 31820306
J Cell Biochem. 2020 Oct;121(10):4271-4281
pubmed: 31898365
Eur Spine J. 2019 Feb;28(2):214-223
pubmed: 30324498
Gene. 2019 Feb 20;686:250-260
pubmed: 30453069
Int J Mol Med. 2018 Oct;42(4):2193-2202
pubmed: 30015833
Cancer Manag Res. 2020 Jan 09;12:199-207
pubmed: 32021436
Int J Biochem Cell Biol. 2020 Jan;118:105637
pubmed: 31669140
Occup Environ Med. 2005 Dec;62(12):851-60
pubmed: 16299094
Onco Targets Ther. 2020 Feb 04;13:1073-1086
pubmed: 32099409
Mol Med Rep. 2018 Feb;17(2):3158-3163
pubmed: 29257270
IUBMB Life. 2018 Jun;70(6):479-490
pubmed: 29707878
Int J Immunopathol Pharmacol. 2018 Jan-Dec;32:2058738418759180
pubmed: 29451405
Int J Mol Med. 2018 Jun;41(6):3353-3365
pubmed: 29532887
Ann Rheum Dis. 2014 Jun;73(6):968-74
pubmed: 24665116
J Cell Biochem. 2019 Oct;120(10):17616-17624
pubmed: 31119790
J Cell Mol Med. 2018 Dec;22(12):5768-5775
pubmed: 30188595
J Allergy Clin Immunol. 2018 Apr;141(4):1202-1207
pubmed: 29074454
Biomed Pharmacother. 2018 Aug;104:622-628
pubmed: 29803175
Nat Rev Cancer. 2018 Mar;18(3):187-201
pubmed: 29348578
Int J Mol Med. 2020 Jul;46(1):289-299
pubmed: 32319551
Eur Rev Med Pharmacol Sci. 2019 Nov;23(22):9871-9881
pubmed: 31799655
Sci Rep. 2018 Jan 24;8(1):1512
pubmed: 29367647
Nat Commun. 2020 Mar 20;11(1):1507
pubmed: 32198345
Nat Rev Mol Cell Biol. 2015 Jun;16(6):329-44
pubmed: 25991373
Brief Bioinform. 2014 Jan;15(1):1-19
pubmed: 23175680
Mol Med Rep. 2019 Jul;20(1):375-387
pubmed: 31115518
Biomed Res Int. 2016;2016:3684875
pubmed: 28097131
Int J Mol Med. 2019 Oct;44(4):1357-1365
pubmed: 31432092
Biol Chem. 2018 Mar 28;399(4):387-395
pubmed: 29261512
J Orthop Res. 2020 Nov;38(11):2521-2531
pubmed: 32091156
Cancer Lett. 2013 Oct 10;339(2):159-66
pubmed: 23791884
Clin Orthop Relat Res. 2015 Jun;473(6):1903-12
pubmed: 25024024
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
Aging (Albany NY). 2019 May 6;11(9):2610-2627
pubmed: 31061236
Int J Mol Med. 2019 Jan;43(1):583-592
pubmed: 30387830
Int Immunopharmacol. 2017 Feb;43:236-242
pubmed: 28043032
Curr Pharm Biotechnol. 2020;21(13):1394-1401
pubmed: 32196445
Cancer Med. 2019 Oct;8(13):6064-6081
pubmed: 31436388
BMC Musculoskelet Disord. 2020 Mar 6;21(1):149
pubmed: 32143617
Aging (Albany NY). 2018 Jan 18;10(1):131-143
pubmed: 29348392
Curr Mol Biol Rep. 2018;4(4):143-150
pubmed: 30464887
Biochem Biophys Res Commun. 2019 Jun 18;514(1):316-322
pubmed: 31036320
J Spinal Disord. 2000 Jun;13(3):205-17
pubmed: 10872758
EBioMedicine. 2019 Oct;48:619-629
pubmed: 31631036