The Outcome of Fungal Pneumonia with Hematological Cancer.

Fungal pneumonia Hematological cancer Intensive care

Journal

Infection & chemotherapy
ISSN: 2093-2340
Titre abrégé: Infect Chemother
Pays: Korea (South)
ID NLM: 101531537

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 24 06 2020
accepted: 11 10 2020
entrez: 30 12 2020
pubmed: 31 12 2020
medline: 31 12 2020
Statut: ppublish

Résumé

Fungal pneumonia is a common infectious complication of hematological cancer (HC) patients. In this retrospective study, the objective was set to identify the risk factors and outcome of fungal pneumonia in adult HC patients. This retrospective study was conducted with adult (>16 years) HC patients from January 2017 and December 2018. During the study period, of 181 patients included 76 were diagnosed with fungal pneumonia. The most common HC was identified as acute myeloid leukaemia (40%). Of the participating patients, 52 (29%) were hematopoietic stem cell transplant (HSCT) recipients. The median age of patients with fungal pneumonia was significantly greater: 57 Fungal pneumonia is a lethal complication in HC patients. Intensive care need is the most important predictive factor for mortality.

Sections du résumé

BACKGROUND BACKGROUND
Fungal pneumonia is a common infectious complication of hematological cancer (HC) patients. In this retrospective study, the objective was set to identify the risk factors and outcome of fungal pneumonia in adult HC patients.
MATERIALS AND METHODS METHODS
This retrospective study was conducted with adult (>16 years) HC patients from January 2017 and December 2018.
RESULTS RESULTS
During the study period, of 181 patients included 76 were diagnosed with fungal pneumonia. The most common HC was identified as acute myeloid leukaemia (40%). Of the participating patients, 52 (29%) were hematopoietic stem cell transplant (HSCT) recipients. The median age of patients with fungal pneumonia was significantly greater: 57
CONCLUSION CONCLUSIONS
Fungal pneumonia is a lethal complication in HC patients. Intensive care need is the most important predictive factor for mortality.

Identifiants

pubmed: 33377321
pii: 52.530
doi: 10.3947/ic.2020.52.4.530
pmc: PMC7779983
doi:

Types de publication

Journal Article

Langues

eng

Pagination

530-538

Informations de copyright

Copyright © 2020 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS.

Déclaration de conflit d'intérêts

No conflicts of interest.

Références

Shock. 2013 Mar;39(3):250-4
pubmed: 23364436
J Clin Oncol. 2018 Oct 20;36(30):3043-3054
pubmed: 30179565
J Crit Care. 2012 Dec;27(6):739.e1-6
pubmed: 23217573
Clin Microbiol Infect. 2012 Mar;18(3):268-81
pubmed: 21793988
Haematologica. 2000 Dec;85(12):1255-60
pubmed: 11114131
Intensive Care Med. 2012 Sep;38(9):1505-13
pubmed: 22592633
Gac Med Mex. 2016 Jul-Aug;152(4):465-72
pubmed: 27595249
Mediterr J Hematol Infect Dis. 2017 Jan 01;9(1):e2017012
pubmed: 28101316
Aust Crit Care. 2018 Nov;31(6):363-368
pubmed: 29429570
Infect Dis Clin North Am. 2019 Jun;33(2):289-309
pubmed: 30935703
JAMA. 2016 Feb 23;315(8):801-10
pubmed: 26903338
J Clin Oncol. 2013 Aug 1;31(22):2810-8
pubmed: 23752112
Hematology. 2015 Jun;20(5):247-53
pubmed: 25310461
Diagn Interv Imaging. 2013 Feb;94(2):193-201
pubmed: 23313163
Clin Chest Med. 2017 Sep;38(3):479-491
pubmed: 28797490
Eur J Intern Med. 2011 Feb;22(1):57-61
pubmed: 21238895
Dis Mon. 2012 Apr;58(4):239-49
pubmed: 22449371
Bone Marrow Transplant. 2011 Sep;46(9):1186-91
pubmed: 21042315
J Clin Oncol. 2016 Mar 20;34(9):987-1011
pubmed: 26846975
Curr Opin Anaesthesiol. 2017 Apr;30(2):200-204
pubmed: 28207566
Clin Infect Dis. 2008 Jun 15;46(12):1813-21
pubmed: 18462102
Crit Care Med. 2006 May;34(5):1297-310
pubmed: 16540951

Auteurs

Esma Eren (E)

Kayseri City Hospital, Infectious Disease Clinic, Kayseri, Turkey. esmaereneryilmaz@gmail.com.

Emine Alp (E)

Ministry of Health, Ankara, Turkey.

Fatma Cevahir (F)

Unıversıty of Sakarya Applıed Scıences, Akyazı Vocational School of Health Services, Medical Services and Techniques Department, Sakarya, Turkey.

Tuğba Tok (T)

Erciyes University, Faculty of Medicine, Department of Infectious Disease and Clinical Microbiology, Kayseri, Turkey.

Ayşegül Ulu Kılıç (AU)

Erciyes University, Faculty of Medicine, Department of Infectious Disease and Clinical Microbiology, Kayseri, Turkey.

Leylagül Kaynar (L)

Erciyes University, Faculty of Medicine, Department of Internal Medicine, Hematology, Kayseri, Turkey.

Recep Civan Yüksel (RC)

Kayseri City Hospital, Intensive Care Unit, Kayseri, Turkey.

Classifications MeSH