Application of radiochromic gel dosimetry to commissioning of a megavoltage research linear accelerator for small-field animal irradiation studies.


Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
Mar 2021
Historique:
revised: 25 11 2020
received: 01 05 2020
accepted: 17 12 2020
pubmed: 31 12 2020
medline: 15 5 2021
entrez: 30 12 2020
Statut: ppublish

Résumé

To develop and implement an efficient and accurate commissioning procedure for small-field static beam animal irradiation studies on an MV research linear accelerator (Linatron-M9) using radiochromic gel dosimetry. The research linear accelerator (Linatron-M9) is a 9 MV linac with a static fixed collimator opening of 5.08 cm diameter. Lead collimators were manually placed to create smaller fields of 2 × 2 cm Absolute dosimetry measurements were confirmed within 1.4% (k = 2, 95% confidence = 5%). The relative output factor of the small fields measured with films and gels agreed with a maximum relative percent error difference between the two methods of 1.1 % for the 1 × 1 cm This work provides a commissioning process to measure the beam characteristics of a fixed beam MV accelerator with detailed dosimetric evaluation for its implementation in megavoltage small animal irradiation studies. Radiochromic gel dosimeters are efficient small-field relative dosimetry tools providing 3D dose measurements allowing for full representation of dose, dosimeter misalignment corrections and high reproducibility with low inter-dosimeter variability. Overall, radiochromic gels are valuable for fast, full relative dosimetry commissioning in comparison to films for application in high-energy small-field animal irradiation studies.

Identifiants

pubmed: 33378092
doi: 10.1002/mp.14685
pmc: PMC8917956
mid: NIHMS1782192
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1404-1416

Subventions

Organisme : NCI NIH HHS
ID : R37 CA222215
Pays : United States
Organisme : Hadramout Establishment for Human Development
Organisme : Academic Research Initiative
ID : 2016-DN-077-ARI106
Organisme : NIH HHS
ID : R37CA222215
Pays : United States

Informations de copyright

© 2020 American Association of Physicists in Medicine.

Références

Phys Med Biol. 2011 Apr 21;56(8):2585-99
pubmed: 21444969
Phys Med Biol. 2013 Sep 21;58(18):6241-62
pubmed: 23965800
Phys Med Biol. 2011 Mar 7;56(5):1259-79
pubmed: 21285484
Br J Radiol. 2000 Jan;73(865):58-65
pubmed: 10721321
Med Phys. 2006 Apr;33(4):850-8
pubmed: 16696460
Cancers (Basel). 2019 Feb 01;11(2):
pubmed: 30717307
Phys Med Biol. 1984 Oct;29(10):1189-97
pubmed: 6494247
Med Phys. 1994 Jul;21(7):1093-121
pubmed: 7968843
Med Phys. 2018 May;45(5):2252-2265
pubmed: 29542820
Med Phys. 2006 May;33(5):1338-45
pubmed: 16752569
Med Phys. 1998 Sep;25(9):1741-50
pubmed: 9775382
Phys Med Biol. 2010 Mar 7;55(5):R1-63
pubmed: 20150687
Medicine (Baltimore). 2017 Dec;96(48):e8452
pubmed: 29310329
Med Phys. 2011 Feb;38(2):845-56
pubmed: 21452722
Int J Radiat Oncol Biol Phys. 2008 Aug 1;71(5):1591-9
pubmed: 18640502
Technol Cancer Res Treat. 2017 Feb;16(1):45-56
pubmed: 26792490
Med Phys. 1999 Sep;26(9):1847-70
pubmed: 10505874
Phys Med Biol. 2007 Aug 7;52(15):4697-706
pubmed: 17634658
Phys Med Biol. 2009 Sep 7;54(17):5341-57
pubmed: 19687532
Med Phys. 2006 Jul;33(7):2506-18
pubmed: 16898454
Med Phys. 2014 Mar;41(3):031501
pubmed: 24593704
World J Radiol. 2017 Mar 28;9(3):112-125
pubmed: 28396725
Phys Med Biol. 2010 Mar 7;55(5):1279-93
pubmed: 20134082
Phys Med Biol. 2005 Jul 7;50(13):N135-40
pubmed: 15972974
Med Phys. 2001 Jun;28(6):868-93
pubmed: 11439485
Med Phys. 2014 Mar;41(3):031714
pubmed: 24593718
Med Phys. 2011 Dec;38(12):6754-62
pubmed: 22149857
Phys Med Biol. 2006 Feb 7;51(3):653-73
pubmed: 16424587
Radiother Oncol. 2018 Mar;126(3):471-478
pubmed: 29269093
Med Phys. 2007 Dec;34(12):4706-16
pubmed: 18196798
Phys Med Biol. 2018 Jul 09;63(14):145001
pubmed: 29923495
Med Phys. 1998 Nov;25(11):2093-115
pubmed: 9829234
Australas Phys Eng Sci Med. 2019 Jun;42(2):541-551
pubmed: 30989595
Int J Radiat Oncol Biol Phys. 2020 Jul 1;107(3):587-596
pubmed: 32169408
Phys Med Biol. 2009 Oct 7;54(19):5847-60
pubmed: 19741277
Med Phys. 2018 Nov;45(11):e1123-e1145
pubmed: 30247757
Phys Med Biol. 1996 Dec;41(12):2705-17
pubmed: 8971964
Int J Radiat Oncol Biol Phys. 2010 Jul 1;77(3):886-94
pubmed: 20510199
Phys Med Biol. 2011 Jun 21;56(12):R55-83
pubmed: 21617291
Med Phys. 2001 Jul;28(7):1436-45
pubmed: 11488576
Phys Med. 2018 Aug;52:154-164
pubmed: 30139604
Int J Radiat Biol. 2011 Oct;87(10):1001-10
pubmed: 21961967

Auteurs

Noora Ba Sunbul (N)

Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.

Ibrahim Oraiqat (I)

Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.

Benjamin Rosen (B)

Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.

Cameron Miller (C)

Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.

Christopher Meert (C)

Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.

Martha M Matuszak (MM)

Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.

Shaun Clarke (S)

Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.

Sara Pozzi (S)

Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.

Jean M Moran (JM)

Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.

Issam El Naqa (I)

Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.

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