Malignant phyllodes tumor with liposarcomatous differentiation: Diagnosed on cytology.
FNAC
liposarcoma
malignant
phyllodes tumor I heterologous element
Journal
Diagnostic cytopathology
ISSN: 1097-0339
Titre abrégé: Diagn Cytopathol
Pays: United States
ID NLM: 8506895
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
revised:
07
11
2020
received:
12
09
2020
accepted:
07
12
2020
pubmed:
31
12
2020
medline:
19
11
2021
entrez:
30
12
2020
Statut:
ppublish
Résumé
Phyllodes tumor (PT) accounts for less than 1% of all primary tumors of the breast and 2% to 3% of all fibroepithelial lesions. We report a case of heterologous liposarcomatous elements in a malignant PT of the breast on Fine needle aspiration cytology (FNAC) and later confirmed by histopathological examination. A 58-years-old woman presented with a huge breast mass for which FNAC was done. Cytology showed features of malignant PT with a good representation of heterologous liposarcomatous areas. The cytological findings were in concordance with the histologic features. Malignant PT and its various heterologous elements of stroma can be diagnosed on FNA cytology when performed optimally. They can be vital for the preoperative assessment of patients suspected with malignancy to formulate the surgical plan accordingly.
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
E226-E230Informations de copyright
© 2020 Wiley Periodicals LLC.
Références
Bernstein L, Deapen D, Ross RK. The descriptive epidemiology of malignant cystosarcoma phyllodes tumors of the breast. Cancer. 1993;71(10):3020-3024.
Scolyer RA, McKenzie PR, Achmed D, Lee CS. Can phyllodes tumours of the breast be distinguished from fibroadenomas using fine needle aspiration cytology? Pathology. 2001;33(4):437-443.
Rungta S, Kleer CG. Metaplastic carcinomas of the breast: diagnostic challenges and new translational insights. Arch Pathol Lab Med. 2012;136(8):896-900.
Qizilbash AH. Cystosarcoma phyllodes with liposarcomatous stroma. Am J Clin Pathol. 1976;65(3):321-327.
Lester J, Stout AP. Cystosarcoma phyllodes. Cancer. 1954;7(2):335-353.
Mishra SP, Tiwary SK, Mishra M, Khanna AK. Phyllodes tumor of breast: a review article. ISRN Surg. 2013;2013:1-10. http://dx.doi.org/10.1155/2013/361469.
Isotalo PA, George RL, Walker R, SenGupta SK. Malignant phyllodes tumor with liposarcomatous differentiation. Arch Pathol Lab Med. 2005;129(3):421-422.
Hawkins RE, Schofield JB, Fisher C, Wiltshaw E, McKinna JA. The clinical and histologic criteria that predict metastases from cystosarcoma phyllodes. Cancer. 1992;69(1):141-147.
Zurrida S, Bartoli C, Galimberti V, et al. Which therapy for unexpected phyllode tumour of the breast? Eur J Cancer Oxf Engl. 1992;28(2-3):654-657.
Uriev L, Maslovsky I, Vainshtein P, Yoffe B, Ben-Dor D. Malignant phyllodes tumor with heterologous liposarcomatous differentiation and tubular adenoma-like epithelial component. Int J Med Sci. 2006;3(4):130-134.
Jinkala S, Neelaiah S, Badhe BA. Role of fine needle aspiration in the diagnosis of metaplastic carcinoma of breast. Ann Pathol Lab Med. 2018;5(7):96-99.
Vera-Alvarez J, Marigil-Gómez M, Abascal-Agorreta M, García-Prats MD, López-López JI, Pérez-Ruiz J. Malignant phyllodes tumor with pleomorphic liposarcomatous stroma diagnosed by fine needle aspiration cytology: a case report. Acta Cytol. 2002;46(1):50-56.
Vm V-H, Vmv A. Phyllodes tumors (cystosarcoma phyllodes): a diagnostic and therapeutic challenge. World J Breast Cancer Res. 2019;2(2):1016.
Onkendi EO, Jimenez RE, Spears GM, Harmsen WS, Ballman KV, Hieken TJ. Surgical treatment of borderline and malignant phyllodes tumors: the effect of the extent of resection and tumor characteristics on patient outcome. Ann Surg Oncol. 2014;21(10):3304-3309.