Clinical features and laboratory characteristics of patients hospitalized with COVID-19: single centre report from Egypt.
Adolescent
Adult
Age Factors
Asymptomatic Infections
/ epidemiology
COVID-19
/ diagnostic imaging
Child
Egypt
/ epidemiology
Female
Hospitalization
Humans
Lymphocytes
/ cytology
Male
Middle Aged
Neutrophils
/ cytology
Retrospective Studies
Risk Factors
Severity of Illness Index
Tomography, X-Ray Computed
Young Adult
COVID-19
Egypt
SARS-CoV-2
age group
clinical presentation
coronavirus
Journal
Journal of infection in developing countries
ISSN: 1972-2680
Titre abrégé: J Infect Dev Ctries
Pays: Italy
ID NLM: 101305410
Informations de publication
Date de publication:
31 12 2020
31 12 2020
Historique:
received:
27
05
2020
accepted:
10
09
2020
entrez:
30
12
2020
pubmed:
31
12
2020
medline:
23
1
2021
Statut:
epublish
Résumé
The recently discovered novel coronavirus disease (COVID-19) has emerged in Wuhan, China, since January 2020. Egypt reported a low incidence of infection when compared with other countries. The aim of the study was to assess the characterization of COVID-19 infection among the Egyptian population. Data were collected from a single COVID-19 quarantine hospital in Cairo. A total number of 195 cases were included with their clinical, laboratory, and radiological data. Three different age groups behaved differently for COVD-19 infection. The pediatric age group was asymptomatic entirely, the middle age group (18-50 years) were asymptomatic in 53.3% of cases, while 77.9% of those above 50 years were symptomatic (p ≤ 0.001). The latter group had a high incidence of COVID-pneumonia in (83.1%), and moderate to critical presentations were encountered in 66.3% of them. Neutrophil to lymphocyte (N/L) ratio correlated directly with the age and case severity. C-reactive protein (CRP) and computed tomography scan chest (CT-chest) had added value on COVID-19 diagnosis in suspected cases. In Egypt, patients above 50 years are at a higher risk for symptomatic COVID-19 infection and leaner for moderate to critical COVID-19 presentation. The triad of CT-chest, CRP, and N/L ratio could be an integrated panel for assessing disease severity.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1352-1360Informations de copyright
Copyright (c) 2020 Mohamed El Kassas, Noha Asem, Amr Abdelazeem, Ahmad Madkour, Hamdy Sayed, Ahmed Tawheed, Ahmed Al Shafie, Mahmoud Gamal, Hassan Elsayed, Mohamed Badr, Mohamed Hassany, Dalia Omran, Amr El Fouly.
Déclaration de conflit d'intérêts
No Conflict of Interest is declared