Effectiveness of metronidazole gel and mobile telephone short-message service reminders on gingivitis in orthodontic patients.
Gingivitis
Metronidazole
Oral hygiene
Orthodontic appliances
Text messaging
Journal
The Angle orthodontist
ISSN: 1945-7103
Titre abrégé: Angle Orthod
Pays: United States
ID NLM: 0370550
Informations de publication
Date de publication:
01 03 2021
01 03 2021
Historique:
accepted:
01
10
2020
received:
01
05
2020
pubmed:
31
12
2020
medline:
23
3
2021
entrez:
30
12
2020
Statut:
ppublish
Résumé
To compare the effectiveness of metronidazole gel and mobile telephone short-message service (SMS) reminders on gingivitis in patients undergoing fixed orthodontic treatment. The trial was double blinded (patient and investigator), and only the clinical trial unit pharmacist was unblinded. Data were collected from patients undergoing fixed orthodontic treatment for at least 6 months. A total of 66 patients were randomly assigned to either 0.8% metronidazole gel (n = 22), SMS reminder and placebo gel (n = 22), or placebo (control) group only (n = 22). Gingival index (GI), bleeding index (BI), and orthodontic plaque index (OPI) were evaluated on several teeth at baseline (T0) and after 4 weeks (T1). Paired-sample t-tests were used to compare mean differences of indexes at T0 and T1 in the groups, and independent-sample t-tests were used to determine the effects of interventions compared with the controls. Data from 64 patients were analyzed; there were 2 dropouts. There were statistically significant (P < .05) reductions in GI, BI, and OPI scores from T0 to T1 for each intervention. However, there were no significant differences between each intervention and the control group. There were no adverse effects. The null hypothesis could not be rejected. There is no difference between interventions (application of 0.8% metronidazole gel and SMS reminder for reinforcing oral hygiene) in reducing gingival inflammation in orthodontic patients.
Identifiants
pubmed: 33378447
pii: 450145
doi: 10.2319/052920-490.1
pmc: PMC8028492
doi:
Substances chimiques
Metronidazole
140QMO216E
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
220-226Informations de copyright
© 2021 by The EH Angle Education and Research Foundation, Inc.
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