Effectiveness of Terlipressin on Modulation of Portal Vein Pressure after Hepatic Resections in Non-Cirrhotic Patients. A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
majorhepatectomy
majorliverresection
portalveinpressure
randomisedcontrolledtrials
terlipressin
Journal
Chirurgia (Bucharest, Romania : 1990)
ISSN: 1221-9118
Titre abrégé: Chirurgia (Bucur)
Pays: Romania
ID NLM: 9213031
Informations de publication
Date de publication:
Historique:
accepted:
01
12
2020
entrez:
30
12
2020
pubmed:
31
12
2020
medline:
26
1
2021
Statut:
ppublish
Résumé
Background-Objectives: It has been reported, that high posthepatectomy portal vein pressure (PVP) has deleterious effect on the liver parenchyma and causes posthepatectomy liver failure (PHLF) and increased 90-day mortality. Terlipressin, is widely used to mitigate the effects of portal hyper-tension. Randomised clinical trials (RCTs) demonstrated encouraging results of use of terlipressin for modulation of increased posthepatectomy PVP. The aim of the present study was to evaluate the effectiveness of the pharmacological modulation of the increased posthepatectomy PVP after major hepatectomy.
Identifiants
pubmed: 33378629
pii: 1
doi: 10.21614/chirurgia.115.6.707
doi:
pii:
Substances chimiques
Cardiovascular Agents
0
Terlipressin
7Z5X49W53P
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
707-714Informations de copyright
Celsius.