Tall Cell Variant versus Conventional Papillary Thyroid Carcinoma: A Retrospective Analysis in 351 Consecutive Patients.
conventional papillary thyroid carcinoma
tall cell variant of papillary thyroid carcinoma
thyroid surgery
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
28 Dec 2020
28 Dec 2020
Historique:
received:
24
11
2020
revised:
12
12
2020
accepted:
22
12
2020
entrez:
31
12
2020
pubmed:
1
1
2021
medline:
1
1
2021
Statut:
epublish
Résumé
The aim of this retrospective study was to investigate clinical and pathological characteristics of the tall cell variant of papillary thyroid carcinoma compared to conventional variants. The clinical records of patients who underwent surgical treatment between 2009 and 2015 were analyzed. The patients were divided into two groups: those with a histopathological diagnosis of tall cell papillary carcinoma were included in Group A, and those with a diagnosis of conventional variants in Group B. A total of 35 patients were included in Group A and 316 in Group B. All patients underwent total thyroidectomy. Central compartment and lateral cervical lymph node dissection were performed more frequently in Group A (42.8% vs. 18%, Tall cell papillary carcinoma is the most frequent aggressive variant of papillary thyroid cancer. Tall cell histology represents an independent poor prognostic factor compared to conventional variants.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of this retrospective study was to investigate clinical and pathological characteristics of the tall cell variant of papillary thyroid carcinoma compared to conventional variants.
METHODS
METHODS
The clinical records of patients who underwent surgical treatment between 2009 and 2015 were analyzed. The patients were divided into two groups: those with a histopathological diagnosis of tall cell papillary carcinoma were included in Group A, and those with a diagnosis of conventional variants in Group B.
RESULTS
RESULTS
A total of 35 patients were included in Group A and 316 in Group B. All patients underwent total thyroidectomy. Central compartment and lateral cervical lymph node dissection were performed more frequently in Group A (42.8% vs. 18%,
CONCLUSIONS
CONCLUSIONS
Tall cell papillary carcinoma is the most frequent aggressive variant of papillary thyroid cancer. Tall cell histology represents an independent poor prognostic factor compared to conventional variants.
Identifiants
pubmed: 33379135
pii: jcm10010070
doi: 10.3390/jcm10010070
pmc: PMC7794904
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Thyroid. 2007 Jul;17(7):655-61
pubmed: 17696836
Langenbecks Arch Surg. 2004 Aug;389(4):278-82
pubmed: 15164288
Cancer. 2000 Apr 15;88(8):1902-8
pubmed: 10760768
Diagn Cytopathol. 2014 Jan;42(1):11-7
pubmed: 23754825
Am J Surg Pathol. 2006 Feb;30(2):216-22
pubmed: 16434896
Thyroid. 2013 Oct;23(10):1305-11
pubmed: 23600998
Mod Pathol. 2013 Jan;26(1):62-70
pubmed: 22918165
Endocr Connect. 2018 Dec 1;7(12):R286-R293
pubmed: 30352403
World J Surg. 1997 Jan;21(1):15-20; discussion 20-1
pubmed: 8943172
Am J Surg. 1994 Nov;168(5):459-61
pubmed: 7977973
Horm Metab Res. 2009 Jun;41(6):482-7
pubmed: 19370505
Cancer. 1998 Feb 15;82(4):740-53
pubmed: 9477108
Endocr Pract. 2004 May-Jun;10(3):234-41
pubmed: 15310542
Cancer. 1993 Nov 1;72(9):2680-5
pubmed: 8402490
Thyroid. 2008 Nov;18(11):1179-81
pubmed: 18925842
Int J Surg Oncol. 2013;2013:625193
pubmed: 24282633
Thyroid. 2014 Apr;24(4):662-70
pubmed: 24262069
Ann Diagn Pathol. 2009 Jun;13(3):189-96
pubmed: 19433299
Semin Diagn Pathol. 1995 Aug;12(3):249-55
pubmed: 8545591
Hum Pathol. 1992 Dec;23(12):1395-401
pubmed: 1468777
Int J Surg. 2016 Sep;33 Suppl 1:S159-63
pubmed: 27393960
Acta Cytol. 2013;57(5):534-42
pubmed: 24021475
J Clin Endocrinol Metab. 2016 Jan;101(1):264-74
pubmed: 26529630
Endocr Pathol. 2010 Mar;21(1):12-5
pubmed: 20174895
Ann Surg Oncol. 2019 Aug;26(8):2533-2539
pubmed: 31115855
Surgery. 2013 Dec;154(6):1331-6; discussion 1336
pubmed: 24238051
J Thyroid Res. 2010 Jul 26;2010:325602
pubmed: 21048837
Int J Surg. 2014;12 Suppl 2:S140-S143
pubmed: 25183640
Cleve Clin Q. 1976 WINTER;43(4):207-15
pubmed: 1000814
Thyroid. 2009 Nov;19(11):1167-214
pubmed: 19860577
Histopathology. 2012 Jun;60(7):1052-9
pubmed: 22335197
J Pak Med Assoc. 1998 May;48(5):133-7
pubmed: 9813974
J Clin Endocrinol Metab. 2000 Jan;85(1):175-8
pubmed: 10634383
Otolaryngol Head Neck Surg. 2000 Mar;122(3):352-7
pubmed: 10699809
J Surg Oncol. 2004 Apr 1;86(1):44-54
pubmed: 15048680
Am J Surg Pathol. 1988 Jan;12(1):22-7
pubmed: 3337337
J Clin Endocrinol Metab. 2010 Sep;95(9):4197-205
pubmed: 20631031
Am J Surg Pathol. 1999 Feb;23(2):205-11
pubmed: 9989848
Laryngoscope. 2008 Jan;118(1):32-8
pubmed: 18025951
Front Endocrinol (Lausanne). 2020 Aug 25;11:551
pubmed: 32982963
World J Surg. 2008 Jul;32(7):1535-43; discussion 1544-5
pubmed: 18224467
Thyroid. 2002 Aug;12(8):707-11
pubmed: 12225639
Ann Surg Oncol. 2009 Feb;16(2):240-5
pubmed: 19034577
Int J Surg Pathol. 2007 Jan;15(1):14-9
pubmed: 17172492