Esophageal adenocarcinoma after sleeve gastrectomy: actual or potential threat? Italian series and literature review.
Barrett’s esophagus
Esophageal adenocarcinoma
GERD
Sleeve gastrectomy
Journal
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
ISSN: 1878-7533
Titre abrégé: Surg Obes Relat Dis
Pays: United States
ID NLM: 101233161
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
27
07
2020
revised:
23
11
2020
accepted:
23
11
2020
pubmed:
1
1
2021
medline:
25
5
2021
entrez:
31
12
2020
Statut:
ppublish
Résumé
Sleeve gastrectomy (SG) leads to esophageal mucosal damage in an elevated percentage of cases, configuring a clinical condition of Barrett's esophagus (BE) in a proportion as high as 15-18.8%. BE may rarely evolve into esophageal adenocarcinoma (EAC). To raise awareness of BE as a precancerous lesion which may progress toward malignancy after this popular bariatric procedure. Bariatric referral centers, Italy. All patients referred to our bariatric center who developed an EAC after SG between 2012 and 2019 were reviewed and consecutively included in this study. The available scientific literature regarding this complication is additionally reviewed. The 3 male patients comprised in this case series underwent laparoscopic SG between 2012 and 2015 in different bariatric referral centers. Age and body mass index at baseline ranged from 21-54 years and 43.1-75.6 kg/m Although the rate and probability of progression from BE to EAC is still not well defined, assuming that the rising popularity and execution of SG leads to a growth in the BE incidence, then the preoperative identification and stratification of cancer risk factors in this subset of patients is strongly encouraged. Clinical and endoscopic follow-ups are essential to allow for prevention and early diagnosis and for epidemiologic data collection purposes.
Sections du résumé
BACKGROUND
BACKGROUND
Sleeve gastrectomy (SG) leads to esophageal mucosal damage in an elevated percentage of cases, configuring a clinical condition of Barrett's esophagus (BE) in a proportion as high as 15-18.8%. BE may rarely evolve into esophageal adenocarcinoma (EAC).
OBJECTIVES
OBJECTIVE
To raise awareness of BE as a precancerous lesion which may progress toward malignancy after this popular bariatric procedure.
SETTING
METHODS
Bariatric referral centers, Italy.
METHODS
METHODS
All patients referred to our bariatric center who developed an EAC after SG between 2012 and 2019 were reviewed and consecutively included in this study. The available scientific literature regarding this complication is additionally reviewed.
RESULTS
RESULTS
The 3 male patients comprised in this case series underwent laparoscopic SG between 2012 and 2015 in different bariatric referral centers. Age and body mass index at baseline ranged from 21-54 years and 43.1-75.6 kg/m
CONCLUSION
CONCLUSIONS
Although the rate and probability of progression from BE to EAC is still not well defined, assuming that the rising popularity and execution of SG leads to a growth in the BE incidence, then the preoperative identification and stratification of cancer risk factors in this subset of patients is strongly encouraged. Clinical and endoscopic follow-ups are essential to allow for prevention and early diagnosis and for epidemiologic data collection purposes.
Identifiants
pubmed: 33380354
pii: S1550-7289(20)30684-5
doi: 10.1016/j.soard.2020.11.023
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
848-854Commentaires et corrections
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Informations de copyright
Copyright © 2020 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.