Comparison of Two Dosing Regimens of Miltefosine, Both in Combination With Allopurinol, on Clinical and Parasitological Findings of Dogs With Leishmaniosis: A Pilot Study.
canine leishmaniosis
combination therapy
digestive tolerance
modified miltefosine dosage
treatment efficacy
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2020
2020
Historique:
received:
30
06
2020
accepted:
19
11
2020
entrez:
31
12
2020
pubmed:
1
1
2021
medline:
1
1
2021
Statut:
epublish
Résumé
Miltefosine (MIL)-allopurinol combination therapy administered at standard dosage is effective to treat canine leishmaniosis, nevertheless for some dogs the digestive tolerance of MIL is not acceptable. This study evaluates an alternative therapeutic protocol by using a modified dosage of MIL to increase its effectiveness and improve the digestive tolerance. Thirty-four
Identifiants
pubmed: 33381534
doi: 10.3389/fvets.2020.577395
pmc: PMC7767967
doi:
Types de publication
Journal Article
Langues
eng
Pagination
577395Informations de copyright
Copyright © 2020 Iarussi, Paradies, Foglia Manzillo, Gizzarelli, Caratozzolo, Navarro, Greco, Rubino, Oliva and Sasanelli.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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