Chemotherapy for Non-Small Cell Lung Cancer in the Intensive Care Unit.
Adenocarcinoma, Mucinous
/ diagnosis
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Biopsy
Bronchoscopy
Carcinoma, Non-Small-Cell Lung
/ diagnosis
Cisplatin
/ therapeutic use
Female
Humans
Intensive Care Units
Lung
/ diagnostic imaging
Lung Neoplasms
/ diagnosis
Middle Aged
Pemetrexed
/ therapeutic use
Treatment Outcome
Chemotherapy
Icu
Mucinous
Nsclc
Ventilated
Journal
Cancer treatment and research communications
ISSN: 2468-2942
Titre abrégé: Cancer Treat Res Commun
Pays: England
ID NLM: 101694651
Informations de publication
Date de publication:
2021
2021
Historique:
received:
28
11
2020
revised:
18
12
2020
accepted:
19
12
2020
pubmed:
1
1
2021
medline:
1
1
2022
entrez:
31
12
2020
Statut:
ppublish
Résumé
patients with non-small-cell lung cancer (NSCLC) admitted to the intensive care unit have poor prognosis. There is limited data on cytotoxic chemotherapy in this setting. The standard of care for these patients is usually best supportive care. 60-year-old previously healthy female was admitted to the ICU with newly diagnosed mucinous adenocarcinoma of the lung. She received cisplatin and pemetrexed while intubated and mechanically ventilated. She was extubated a week later and discharged home after achieving an excellent radiographic and clinical response. in select patients with NSCLC admitted to the ICU due to complications from their malignancy, a trial of cytotoxic chemotherapy may be reasonable. To our knowledge, this is the first case of mucinous NSCLC treated in the ICU.
Sections du résumé
BACKGROUND
patients with non-small-cell lung cancer (NSCLC) admitted to the intensive care unit have poor prognosis. There is limited data on cytotoxic chemotherapy in this setting. The standard of care for these patients is usually best supportive care.
CASE
60-year-old previously healthy female was admitted to the ICU with newly diagnosed mucinous adenocarcinoma of the lung. She received cisplatin and pemetrexed while intubated and mechanically ventilated. She was extubated a week later and discharged home after achieving an excellent radiographic and clinical response.
DISCUSSION
in select patients with NSCLC admitted to the ICU due to complications from their malignancy, a trial of cytotoxic chemotherapy may be reasonable. To our knowledge, this is the first case of mucinous NSCLC treated in the ICU.
Identifiants
pubmed: 33383487
pii: S2468-2942(20)30129-5
doi: 10.1016/j.ctarc.2020.100294
pii:
doi:
Substances chimiques
Pemetrexed
04Q9AIZ7NO
Cisplatin
Q20Q21Q62J
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
100294Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.