MixInYeast: A Multicenter Study on Mixed Yeast Infections.

Candida chrome agar invasive candidiasis mix infections polymicrobial infections yeast

Journal

Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
Titre abrégé: J Fungi (Basel)
Pays: Switzerland
ID NLM: 101671827

Informations de publication

Date de publication:
29 Dec 2020
Historique:
received: 20 11 2020
revised: 20 12 2020
accepted: 21 12 2020
entrez: 1 1 2021
pubmed: 2 1 2021
medline: 2 1 2021
Statut: epublish

Résumé

Invasive candidiasis remains one of the most prevalent systemic mycoses, and several studies have documented the presence of mixed yeast (MY) infections. Here, we describe the epidemiology, clinical, and microbiological characteristics of MY infections causing invasive candidiasis in a multicenter prospective study. Thirty-four centers from 14 countries participated. Samples were collected in each center between April to September 2018, and they were sent to a reference center to confirm identification by sequencing methods and to perform antifungal susceptibility testing, according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST). A total of 6895 yeast cultures were identified and MY occurred in 150 cases (2.2%). Europe accounted for the highest number of centers, with an overall MY rate of 4.2% (118 out of 2840 yeast cultures). Of 122 MY cases, the most frequent combinations were

Identifiants

pubmed: 33383783
pii: jof7010013
doi: 10.3390/jof7010013
pmc: PMC7823447
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Gilead Sciences research and ESCMID study group
ID : NA

Références

Clin Microbiol Infect. 2020 Jul;26(7):833-841
pubmed: 32246995
Open Forum Infect Dis. 2019 Mar 15;6(Suppl 1):S79-S94
pubmed: 30895218
Clin Microbiol Infect. 2008 Apr;14(4):398-405
pubmed: 18190574
Clin Infect Dis. 2015 Dec 1;61 Suppl 6:S612-7
pubmed: 26567278
Transpl Infect Dis. 2016 Dec;18(6):921-931
pubmed: 27643395
Antimicrob Agents Chemother. 2020 Feb 21;64(3):
pubmed: 31871083
Curr Opin Crit Care. 2010 Oct;16(5):445-52
pubmed: 20711075
J Antimicrob Chemother. 2018 Jan 1;73(suppl_1):i4-i13
pubmed: 29304207
Curr Opin Infect Dis. 2014 Dec;27(6):484-92
pubmed: 25304391
Antimicrob Agents Chemother. 2008 Sep;52(9):3092-8
pubmed: 18591282
Med Mycol. 2016 Mar;54(3):256-65
pubmed: 26613703
Diagn Microbiol Infect Dis. 2007 Dec;59(4):401-6
pubmed: 17888612
Clin Infect Dis. 2007 Jun 15;44(12):e109-14
pubmed: 17516389
Diagn Microbiol Infect Dis. 2002 Dec;44(4):353-7
pubmed: 12543540
PLoS Pathog. 2016 Mar 30;12(3):e1005522
pubmed: 27029023
Antimicrob Agents Chemother. 2014;58(3):1529-37
pubmed: 24366741
PLoS One. 2014 Jul 03;9(7):e101510
pubmed: 24991967
Front Microbiol. 2019 Jul 11;10:1585
pubmed: 31354675
Med Mycol. 2018 Aug 1;56(6):770-773
pubmed: 29087478
Clin Microbiol Infect. 2013 Aug;19(8):E343-53
pubmed: 23607326
Mycoses. 2013 Sep;56(5):576-81
pubmed: 23565662
Nat Rev Dis Primers. 2018 May 11;4:18026
pubmed: 29749387
Clin Infect Dis. 2016 Feb 15;62(4):e1-50
pubmed: 26679628
Rev Esp Quimioter. 2019 Aug;32(4):395-397
pubmed: 31327188
J Antimicrob Chemother. 2019 Mar 1;74(3):618-624
pubmed: 30517635
Infection. 2020 Apr;48(2):275-284
pubmed: 32052287
Drugs. 2014 Sep;74(14):1573-85
pubmed: 25255923
Clin Microbiol Infect. 2012 Dec;18 Suppl 7:19-37
pubmed: 23137135

Auteurs

Narda Medina (N)

Mycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain.

Juan Carlos Soto-Debrán (JC)

Mycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain.

Danila Seidel (D)

Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, Germany.
European Diamond Excellence Center for Medical Mycology of the European Confederation of Medical Mycology (ECMM), 50937 Cologne, Germany.
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.

Isin Akyar (I)

Department of Medical Microbiology, Acibadem Mehmet Ali Aydinlar University School of Medicine, 34758 Istanbul, Turkey.
Acibadem Labmed Laboratories, 34752 Istanbul, Turkey.

Hamid Badali (H)

Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari 48157-33971, Iran.

Aleksandra Barac (A)

Clinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.

Stéphane Bretagne (S)

Laboratoire de Parasitologie-Mycologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France.
Department of Infectious Agents, Université de Paris, 75006 Paris, France.

Yasemin Cag (Y)

Istanbul Medeniyet University Goztepe Training and Research Hospital, 34722 Istanbul, Turkey.
Department of Infectious Diseases and Clinical Microbiology, Istanbul Medeniyet University School of Medicine, 34093 Istanbul, Turkey.

Carole Cassagne (C)

Aix-Marseille University, UMR MD3 IP-TPT, 13885 Marseilles, France.

Carmen Castro (C)

Microbiology Service, Clinical Unit of Infectious Diseases and Microbiology, Hospital Universitario Valme, 41014 Sevilla, Spain.

Arunaloke Chakrabarti (A)

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.

Eric Dannaoui (E)

Unité de Parasitologie-Mycologie, Service de Microbiologie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (AP-HP) Université de Paris, 75015 Paris, France.

Celia Cardozo (C)

Hospital Universitario Clínic, 08036 Barcelona, Spain.

Julio Garcia-Rodriguez (J)

Hospital Universitario La Paz, 28046 Madrid, Spain.

Juliette Guitard (J)

Service de Parasitologie-Mycologie, Centre de Recherche Saint-Antoine, CRSA, AP-HP, Hôpital Saint-Antoine, Sorbonne Université, Inserm, 75012 Paris, France.

Petr Hamal (P)

Department of Microbiology, Palacky University, Faculty of Medicine and Dentistry and University Hospital, 775 15 Olomouc, Czech Republic.

Martin Hoenigl (M)

Division of Infectious Diseases and Global Public Health, University of California San Diego, San Diego, CA 92093, USA.

Tomasz Jagielski (T)

Department of Medical Microbiology, Institute of Microbiology, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096 Warsaw, Poland.

Sadegh Khodavaisy (S)

Division of Molecular Biology & Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran 14167-53955, Iran.

Giuliana Lo Cascio (G)

Microbiology and Virology Unit, Department of Pathology and Diagnostic, Azienda Ospedaliera Universitaria Integrata, 30126 Verona, Italy.

María Carmen Martínez-Rubio (MC)

Hospital Universitario de Puerto Real, 11510 Cádiz, Spain.

Joseph Meletiadis (J)

Clinical Microbiology Laboratory, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Haidari, 12462 Athens, Greece.

Patricia Muñoz (P)

Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.
Department of Medicine, Universidad Complutense de Madrid, CIBERES (CB06/06/0058), 28040 Madrid, Spain.

Elżbieta Ochman (E)

Department of Clinical Microbiology, The Maria Skłodowska-Curie Institute of Oncology, W. K. Roentgena 5, 02-781 Warsaw, Poland.

Teresa Peláez (T)

Hospital Universitario Central de Asturias (HUCA), Fundación para la Investigación Biomédica y la Innovación Biosanitaria del Principado de Asturias (FINBA), 33011 Asturias, Spain.

Ana Perez-Ayala Balzola (A)

Microbiology Department, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.

Juergen Prattes (J)

Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.

Emmanuel Roilides (E)

Infectious Diseases Unit, 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration General Hospital, 54642 Thessaloniki, Greece.

Maite Ruíz-Pérez de Pipaón (M)

Department of Infectious Diseases, Microbiology and Preventive Medicine, University Hospital Virgen del Rocío, 41013 Seville, Spain.

Raphael Stauf (R)

Institute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum Nürnberg, Paracelsus Medical University, 90419 Nuremberg, Germany.
Institute of Medical Microbiology, University Hospital Essen, 45122 Essen, Germany.

Jörg Steinmann (J)

Institute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum Nürnberg, Paracelsus Medical University, 90419 Nuremberg, Germany.
Institute of Medical Microbiology, University Hospital Essen, 45122 Essen, Germany.

Ana Isabel Suárez-Barrenechea (AI)

Infectious disease and Clinical Microbiology Department, Virgen Macarena University Hospital, 41009 Sevilla, Spain.

Rocío Tejero (R)

Unit of Microbiology, Hospital Universitario Reina Sofía, 14004 Cordoba, Spain.

Laura Trovato (L)

U.O.C. Laboratory Analysis Unit, A.O.U. "Policlinico-Vittorio Emanuele", 95123 Catania, Italy.
Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Lourdes Viñuela (L)

Servicio de Microbiología Hospital Universitario Río Hortega, 47012 Valladolid, Spain.

Thanwa Wongsuk (T)

Department of Clinical Pathology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok 10300, Thailand.

Iwona Żak (I)

Department of Clinical Microbiology, Children's University Hospital of Cracow, 30-663 Kraków, Poland.

Hossein Zarrinfar (H)

Allergy Research Center, Mashhad University of Medical Sciences, Mashhad 91766-99199, Iran.

Cornelia Lass-Flörl (C)

Department of Hygiene und Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.

Sevtap Arikan-Akdagli (S)

Department of Medical Microbiology, Hacettepe University Medical School, 06100 Ankara, Turkey.

Ana Alastruey-Izquierdo (A)

Mycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain.

Classifications MeSH