Long-Term Consumption of Anthocyanin-Rich Fruit Juice: Impact on Gut Microbiota and Antioxidant Markers in Lymphocytes of Healthy Males.

anthocyanin antioxidant effects intervention study microbiota nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2)

Journal

Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981

Informations de publication

Date de publication:
29 Dec 2020
Historique:
received: 07 12 2020
revised: 22 12 2020
accepted: 23 12 2020
entrez: 1 1 2021
pubmed: 2 1 2021
medline: 2 1 2021
Statut: epublish

Résumé

Polyphenols are considered protective against diseases associated with oxidative stress. Short-term intake of an anthocyanin-rich fruit juice resulted in significantly reduced deoxyribonucleic acid (DNA) strand-breaks in peripheral blood lymphocytes (PBLs) and affected antioxidant markers in healthy volunteers. Consequently, effects of long-term consumption of fruit juice are of particular interest. In focus was the impact on nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2), the Nrf2-regulated genes NAD(P)H quinone oxidoreductase 1 (

Identifiants

pubmed: 33383921
pii: antiox10010027
doi: 10.3390/antiox10010027
pmc: PMC7823698
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : German Ministry of Economics and Technology (via AiF) and the FEI (Forschungskreis der Ernaehrungsindustrie e.V., Bonn,Germany)
ID : cluster project no. 18068 N.

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Auteurs

Isabel Anna Maria Groh (IAM)

Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Waehringerstrasse 38, 1090 Vienna, Austria.
Department of Experimental and Clinical Pharmacology and Pharmacogenomic, Division of Pharmacogenomic, University Hospital of Tuebingen, Wilhelmstrasse 56, 72074 Tuebingen, Germany.

Alessandra Riva (A)

Centre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.

Dominik Braun (D)

Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Waehringerstrasse 38, 1090 Vienna, Austria.

Heidi G Sutherland (HG)

Centre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation University of Technology (QUT), Queensland, 60 Musk Ave., Kelvin Grove, QLD 4059, Australia.

Owen Williams (O)

Centre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.

Tamara Bakuradze (T)

Food Chemistry and Toxicology, Department of Chemistry, University of Kaiserslautern, Erwin-Schroedinger-Strasse 52, D-67663 Kaiserslautern, Germany.

Gudrun Pahlke (G)

Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Waehringerstrasse 38, 1090 Vienna, Austria.

Elke Richling (E)

Food Chemistry and Toxicology, Department of Chemistry, University of Kaiserslautern, Erwin-Schroedinger-Strasse 52, D-67663 Kaiserslautern, Germany.

Larisa M Haupt (LM)

Centre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation University of Technology (QUT), Queensland, 60 Musk Ave., Kelvin Grove, QLD 4059, Australia.

Lyn R Griffiths (LR)

Centre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation University of Technology (QUT), Queensland, 60 Musk Ave., Kelvin Grove, QLD 4059, Australia.

David Berry (D)

Centre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.

Doris Marko (D)

Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Waehringerstrasse 38, 1090 Vienna, Austria.

Classifications MeSH