Maternal dietary patterns and depressive symptoms during pregnancy: The Born in Guangzhou Cohort Study.


Journal

Clinical nutrition (Edinburgh, Scotland)
ISSN: 1532-1983
Titre abrégé: Clin Nutr
Pays: England
ID NLM: 8309603

Informations de publication

Date de publication:
05 2021
Historique:
received: 01 07 2020
revised: 17 11 2020
accepted: 25 11 2020
pubmed: 2 1 2021
medline: 5 10 2021
entrez: 1 1 2021
Statut: ppublish

Résumé

Maternal depression has been reported to be harmful to maternal and child health, and nutrition-mental health interactions may play a key role, but evidence from longitudinal studies throughout pregnancy remains insufficient. This study aimed to investigate the association of maternal dietary patterns with depressive symptoms throughout pregnancy. This study was based in the Born in Guangzhou Cohort Study. Dietary patterns were defined by cluster analysis based on validated food frequency questionnaires in mid-pregnancy. A healthy diet score was also developed based on predefined criteria of existing dietary guidelines. Depressive symptoms were measured by Self-rating Depression Scale (SDS) in both early and late pregnancy, with SDS scores ≥53 defined as having depressive symptoms. Associations of dietary patterns with SDS scores were examined by linear-mixed models; associations of dietary patterns with the odds of having depressive symptoms were examined by mixed-effects logistic models. The associations of the healthy diet score with both dietary patterns and depressive symptoms were also explored. Six dietary patterns were identified in 17,430 pregnant women, namely 'Varied' (n = 3902, 22.4%), 'Vegetables' (n = 3269, 18.8%), 'Meats' (n = 2951, 16.9%), 'Cereals' (n = 2719, 15.6%), 'Milk' (n = 2377, 13.6%), and 'Fruits' (n = 2212, 12.7%). There were 19.3% and 15.7% of participants with depressive symptoms in early and late pregnancy, respectively. Compared with the 'Varied' pattern, all other patterns were associated with lower SDS scores during pregnancy except for 'Cereals' ('Vegetables': adjusted β [aβ] -0.78, 95% CI -1.16, -0.40; 'Meats': aβ -0.48, 95% CI -0.87, -0.09; 'Milk': aβ -0.52, 95% CI -0.94, -0.10; 'Fruits': aβ -0.85, 95% CI -1.27, -0.42). The 'Vegetables' (adjusted OR [aOR] 0.79, 95% CI 0.67, 0.93), 'Milk' (aOR 0.76, 95% CI 0.63, 0.91), and 'Fruits' (aOR 0.77, 95% CI 0.64, 0.93) patterns were associated with lower odds of having depressive symptoms during pregnancy than the 'Varied' pattern. Results for the healthy diet score revealed the healthiness of the 'Vegetables', 'Fruits', and 'Milk' patterns and supported an inverse association between healthy dietary patterns and depressive symptoms throughout pregnancy. Diets rich in vegetables, fruits, nuts, and dairy products had an inverse association with depressive symptoms throughout pregnancy. Our findings add support to the existing dietary guidelines that healthy diets might also have potential benefits to maternal mental health.

Sections du résumé

BACKGROUND & AIMS
Maternal depression has been reported to be harmful to maternal and child health, and nutrition-mental health interactions may play a key role, but evidence from longitudinal studies throughout pregnancy remains insufficient. This study aimed to investigate the association of maternal dietary patterns with depressive symptoms throughout pregnancy.
METHODS
This study was based in the Born in Guangzhou Cohort Study. Dietary patterns were defined by cluster analysis based on validated food frequency questionnaires in mid-pregnancy. A healthy diet score was also developed based on predefined criteria of existing dietary guidelines. Depressive symptoms were measured by Self-rating Depression Scale (SDS) in both early and late pregnancy, with SDS scores ≥53 defined as having depressive symptoms. Associations of dietary patterns with SDS scores were examined by linear-mixed models; associations of dietary patterns with the odds of having depressive symptoms were examined by mixed-effects logistic models. The associations of the healthy diet score with both dietary patterns and depressive symptoms were also explored.
RESULTS
Six dietary patterns were identified in 17,430 pregnant women, namely 'Varied' (n = 3902, 22.4%), 'Vegetables' (n = 3269, 18.8%), 'Meats' (n = 2951, 16.9%), 'Cereals' (n = 2719, 15.6%), 'Milk' (n = 2377, 13.6%), and 'Fruits' (n = 2212, 12.7%). There were 19.3% and 15.7% of participants with depressive symptoms in early and late pregnancy, respectively. Compared with the 'Varied' pattern, all other patterns were associated with lower SDS scores during pregnancy except for 'Cereals' ('Vegetables': adjusted β [aβ] -0.78, 95% CI -1.16, -0.40; 'Meats': aβ -0.48, 95% CI -0.87, -0.09; 'Milk': aβ -0.52, 95% CI -0.94, -0.10; 'Fruits': aβ -0.85, 95% CI -1.27, -0.42). The 'Vegetables' (adjusted OR [aOR] 0.79, 95% CI 0.67, 0.93), 'Milk' (aOR 0.76, 95% CI 0.63, 0.91), and 'Fruits' (aOR 0.77, 95% CI 0.64, 0.93) patterns were associated with lower odds of having depressive symptoms during pregnancy than the 'Varied' pattern. Results for the healthy diet score revealed the healthiness of the 'Vegetables', 'Fruits', and 'Milk' patterns and supported an inverse association between healthy dietary patterns and depressive symptoms throughout pregnancy.
CONCLUSIONS
Diets rich in vegetables, fruits, nuts, and dairy products had an inverse association with depressive symptoms throughout pregnancy. Our findings add support to the existing dietary guidelines that healthy diets might also have potential benefits to maternal mental health.

Identifiants

pubmed: 33384181
pii: S0261-5614(20)30659-2
doi: 10.1016/j.clnu.2020.11.038
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3485-3494

Informations de copyright

Copyright © 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of Interest All authors declare no conflicts of interests.

Auteurs

Peiyuan Huang (P)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Dongmei Wei (D)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Wanqing Xiao (W)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Mingyang Yuan (M)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Niannian Chen (N)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Xueling Wei (X)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Junyi Xie (J)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Jinhua Lu (J)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Xiaoyan Xia (X)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Minshan Lu (M)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Songying Shen (S)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Jianrong He (J)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China.

Xiu Qiu (X)

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Key Clinical Specialty of Woman and Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China; Provincial Clinical Research Center for Child Health, No.9 Jinsui Road, Guangzhou, Guangdong Province, China. Electronic address: xiu.qiu@bigcs.org.

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