Heart Rate Dependency and Inter-Lead Variability of the T Peak - T End Intervals.

ECG lead comparison T wave peak T wave spatial loop heart rate dependency sex differences

Journal

Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006

Informations de publication

Date de publication:
2020
Historique:
received: 17 08 2020
accepted: 14 10 2020
entrez: 1 1 2021
pubmed: 2 1 2021
medline: 2 1 2021
Statut: epublish

Résumé

The electrocardiographic (ECG) assessment of the T peak-T end (Tpe) intervals has been used in many clinical studies, but several related physiological aspects have not been reported. Specifically, the sources of the Tpe differences between different ECG leads have not been systematically researched, the relationship of Tpe duration to underlying heart rate has not been firmly established, and little is known about the mutual correspondence of Tpe intervals measured in different ECG leads. This study evaluated 796,620 10-s 12-lead ECGs obtained from long-term Holters recorded in 639 healthy subjects (311 female) aged 33.8 ± 9.4 years. For each ECG, transformation to orthogonal XYZ lead was used to measure Tpe in the orthogonal vector magnitude (used as a reference for lead-to-lead comparisons) and to construct a three-dimensional T wave loop. The loop roundness was expressed by a ratio between its circumference and length. These ratios were significantly related to the standard deviation of Tpe durations in different ECG leads. At the underlying heart rate of 60 beats per minute, Tpe intervals were shorter in female than in male individuals (82.5 ± 5.6 vs 90.0 ± 6.5 ms,

Identifiants

pubmed: 33384609
doi: 10.3389/fphys.2020.595815
pmc: PMC7769826
doi:

Types de publication

Journal Article

Langues

eng

Pagination

595815

Subventions

Organisme : British Heart Foundation
ID : NH/16/2/32499
Pays : United Kingdom

Informations de copyright

Copyright © 2020 Andršová, Hnatkova, Šišáková, Toman, Smetana, Huster, Barthel, Novotný, Schmidt and Malik.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Irena Andršová (I)

Department of Internal Medicine and Cardiology, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czechia.

Katerina Hnatkova (K)

National Heart and Lung Institute, Imperial College London, London, United Kingdom.

Martina Šišáková (M)

Department of Internal Medicine and Cardiology, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czechia.

Ondřej Toman (O)

Department of Internal Medicine and Cardiology, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czechia.

Peter Smetana (P)

Wilhelminenspital der Stadt Wien, Vienna, Austria.

Katharina M Huster (KM)

Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Petra Barthel (P)

Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Tomáš Novotný (T)

Department of Internal Medicine and Cardiology, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czechia.

Georg Schmidt (G)

Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Marek Malik (M)

National Heart and Lung Institute, Imperial College London, London, United Kingdom.

Classifications MeSH