Evaluation of the periodontal healing of the second mandibular molar distal site following insertion of PRF in the third molar post extraction alveolus.

autologous growth factors bleeding disorder extraction oral surgery platelet-rich fibrin third molar

Journal

Journal of biological regulators and homeostatic agents
ISSN: 0393-974X
Titre abrégé: J Biol Regul Homeost Agents
Pays: Italy
ID NLM: 8809253

Informations de publication

Date de publication:
Historique:
entrez: 2 1 2021
pubmed: 3 1 2021
medline: 9 2 2021
Statut: ppublish

Résumé

The aim of this study was to evaluate the periodontal healing of the distal sites of the mandibular second molars, comparing the extraction therapy of the third molar with and without PRF adjunct into the postextraction alveolus. The study sample was composed by 40 consecutive patients who underwent extraction of mandibular third molars. Patients were divided in two groups: the last 20 participants who have only been subjected to extraction (spontaneous healing group, SHG) and the first 20 patients who had PRF adjunct (PRF group, PG). Healing was evaluated by analyzing the variations in terms of PPD (Probing Pocket Depth), REC (Recession), CAL (Level of Clinical Attachment), BoP (Bleeding on Probing) and GI (Gingival Index) from Baseline to further follow-ups at 1 month and 3 months. The disto-vestibular (DV) and disto-lingual (DL) PPD values of the second mandibular molar were measured at Baseline and after three months in the two groups. Patients of the PG group showed lower PPD values at 1 month and 3 months postoperatively: DV: 3.6±1.09 - DL: 3.5±1.15 and DV: 2.5±0.83 - DL: 2.6±1.09, respectively. Patients belonging to the SHG also showed lower PPD values, reporting respectively the following DV values after 3 months: 2.7±0.86 - DL: 2.75±0. 85. However, there was no statistically significant difference comparing the results obtained in PG and SHG groups at 1 and 3 months (p>0.05). The insertion of PRF inside the post-extraction alveolus of the mandibular third molar leads to limited improvement in terms of periodontal healing, compared to extraction therapy only.

Identifiants

pubmed: 33386040
pii: 10

Types de publication

Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

111-118. Technology in Medicine

Informations de copyright

Copyright 2020 Biolife Sas. www.biolifesas.org.

Auteurs

P C Passarelli (PC)

Department of Head and Neck, Division of Oral Surgery and Implantology, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy.

A Romeo (A)

Department of Head and Neck, Division of Oral Surgery and Implantology, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy.

M A Lopez (MA)

Unit of Otolaryngology, UOS ORL TI, Campus-Biomedico University, Rome, Italy.

P De Angelis (P)

Department of Head and Neck, Division of Oral Surgery and Implantology, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy.

V Desantis (V)

Department of Head and Neck, Division of Oral Surgery and Implantology, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy.

G B Piccirillo (GB)

Department of Head and Neck, Division of Oral Surgery and Implantology, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy.

R Papa (R)

Department of Head and Neck, Division of Oral Surgery and Implantology, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy.

P Papi (P)

Department of Oral and Maxillo-facial Sciences, "Sapienza" University of Rome, Rome, Italy.

G Pompa (G)

Department of Oral and Maxillo-facial Sciences, "Sapienza" University of Rome, Rome, Italy.

A Moffa (A)

Unit of Otolaryngology, UOS ORL TI, Campus-Biomedico University, Rome, Italy.

M Casale (M)

Unit of Otolaryngology, UOS ORL TI, Campus-Biomedico University, Rome, Italy.

A D'Addona (A)

Department of Head and Neck, Division of Oral Surgery and Implantology, Institute of Clinical Dentistry, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Gemelli, Rome, Italy.

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Classifications MeSH