Covid-19 in Man: A Very Dangerous Affair.
Covid 19
SARS-CoV-2
erectile dysfunction
immune system.
male gender
testosterone
Journal
Endocrine, metabolic & immune disorders drug targets
ISSN: 2212-3873
Titre abrégé: Endocr Metab Immune Disord Drug Targets
Pays: United Arab Emirates
ID NLM: 101269157
Informations de publication
Date de publication:
2021
2021
Historique:
received:
30
09
2020
revised:
01
11
2020
accepted:
11
11
2020
pubmed:
4
1
2021
medline:
15
12
2021
entrez:
3
1
2021
Statut:
ppublish
Résumé
The novel pandemic of Coronavirus disease 2019 (COVID-19) has become a public health issue since March 2020, with more than 30 million people found to be infected worldwide. Men may be considered to be at a higher risk of poor prognosis or death once the infection occurred. Concerns surfaced regarding the risk of a possible testicular injury due to SARS-CoV-2 infection. Several data support the existence of a bivalent role of testosterone (T) in driving poor prognosis in patients with COVID-19. On the one hand, this is attributable to the fact that T may facilitate SARS-CoV-2 entry in human cells by means of an enhanced expression of transmembrane serine-protease 2 (TMPRSS
Identifiants
pubmed: 33388025
pii: EMIDDT-EPUB-112943
doi: 10.2174/1871530321666210101123801
doi:
Substances chimiques
Testosterone
3XMK78S47O
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1544-1554Informations de copyright
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