Immunomodulatory Properties of a γ-Aminobutyric Acid-Enriched Strawberry Juice Produced by

GABA Levilactobacillus brevis TLR4 activation anti-inflammatory properties lactic acid bacteria strawberry fermented juice

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2020
Historique:
received: 24 09 2020
accepted: 20 11 2020
entrez: 4 1 2021
pubmed: 5 1 2021
medline: 5 1 2021
Statut: epublish

Résumé

Gamma-aminobutyric acid (GABA) plays a key role in mammals as the major inhibitory neurotransmitter of the central nervous system. Although GABA may not be able to cross the human blood-brain barrier, it was approved as a food ingredient because of its benefits to the host after oral administration including anti-hypertensive, anti-depressant and anti-inflammatory activities. Considering the current trend toward the development of new functional and natural products and that microbial fermentation is one of the most promising methods to produce this non-protein amino acid, the

Identifiants

pubmed: 33391235
doi: 10.3389/fmicb.2020.610016
pmc: PMC7773669
doi:

Types de publication

Journal Article

Langues

eng

Pagination

610016

Informations de copyright

Copyright © 2020 Cataldo, Villena, Elean, Savoy de Giori, Saavedra and Hebert.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Pablo G Cataldo (PG)

Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Argentina.

Julio Villena (J)

Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Argentina.

Mariano Elean (M)

Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Argentina.

Graciela Savoy de Giori (G)

Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Argentina.

Lucila Saavedra (L)

Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Argentina.

Elvira M Hebert (EM)

Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Argentina.

Classifications MeSH