Anti-CD2 Antibody-Coated Nanoparticles Containing IL-2 Induce NK Cells That Protect Lupus Mice
NK cells
autoimmunity
cytokines
immune regulation
immunotherapy
nanoparticles
systemic lupus erythematosus
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2020
2020
Historique:
received:
10
08
2020
accepted:
10
11
2020
entrez:
4
1
2021
pubmed:
5
1
2021
medline:
16
6
2021
Statut:
epublish
Résumé
We recently reported that the treatment with nanoparticles (NPs) loaded with tolerogenic cytokines suppressed the manifestations of lupus-like disease induced by the transfer of donor CD4
Identifiants
pubmed: 33391260
doi: 10.3389/fimmu.2020.583338
pmc: PMC7772200
doi:
Substances chimiques
CD2 Antigens
0
Interleukin-2
0
Transforming Growth Factor beta
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
583338Subventions
Organisme : NIAID NIH HHS
ID : R21 AI154935
Pays : United States
Organisme : NICHD NIH HHS
ID : R21 HD097531
Pays : United States
Informations de copyright
Copyright © 2020 Horwitz, Liu, Bickerton, Castaldo, Matarese, Fahmy and La Cava.
Déclaration de conflit d'intérêts
DH is an officer of General Nanotherapeutics LLC and owns stock. DH and TF own stocks and stock options at Toralgen, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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