Clinical profiles of placenta accreta spectrum: the PACCRETA population-based study.


Journal

BJOG : an international journal of obstetrics and gynaecology
ISSN: 1471-0528
Titre abrégé: BJOG
Pays: England
ID NLM: 100935741

Informations de publication

Date de publication:
Sep 2021
Historique:
accepted: 29 12 2020
pubmed: 5 1 2021
medline: 1 9 2021
entrez: 4 1 2021
Statut: ppublish

Résumé

To describe and compare the characteristics of women with placenta accreta spectrum (PAS) and their pregnancy outcomes according to the presence of placenta praevia and a prior caesarean section. Prospective population-based study. All 176 maternity hospitals of eight French regions. Two hundred and forty-nine women with PAS, from a source population of 520 114 deliveries. Women with PAS were classified into two risk-profile groups, with or without the high-risk combination of placenta praevia (or an anterior low-lying placenta) and at least one prior caesarean. These two groups were described and compared. Population-based incidence of PAS, characteristics of women, pregnancies, deliveries and pregnancy outcomes. The PAS population-based incidence was 4.8/10 000 (95% CI 4.2-5.4/10 000). After exclusion of women lost to follow up from the analysis, the group with placenta praevia and a prior caesarean included 115 (48%) women and the group without this combination included 127 (52%). In the group with both factors, PAS was more often suspected antenatally (77% versus 17%; P < 0.001) and more often percreta (38% versus 5%; P < 0.001). This group also had more hysterectomies (53% versus 21%, P < 0.001) and higher rates of blood product transfusions, maternal complications, preterm births and neonatal intensive care unit admissions. Sensitivity analysis showed similar results after exclusion of women who delivered vaginally. More than half the cases of PAS occurred in women without the combination of placenta praevia and a prior caesarean delivery, and these women had better maternal and neonatal outcomes. We cannot completely rule out that some of the women who delivered vaginally had placental retention rather than PAS; however, we found similar results among women who delivered by caesarean. Half the women with PAS do not have both placenta praevia and a prior caesarean delivery, and they have better maternal outcomes.

Identifiants

pubmed: 33393174
doi: 10.1111/1471-0528.16647
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1646-1655

Subventions

Organisme : Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche
ID : AOR12156

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021 John Wiley & Sons Ltd.

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Auteurs

G Kayem (G)

Trousseau Hospital, APHP, Sorbonne University, Paris, France.
CRESS U1153, INSERM, Obstetrical, Perinatal and Paediatric Epidemiology (EPOPé) Research Team, Université de Paris, Paris, France.

A Seco (A)

CRESS U1153, INSERM, Obstetrical, Perinatal and Paediatric Epidemiology (EPOPé) Research Team, Université de Paris, Paris, France.
Clinical Research Unit Necker Cochin, APHP, Paris, France.

G Beucher (G)

Service de Gynécologie Obstétrique et Médecine de la Reproduction, CHU de Caen, Caen Cedex, France.

C Dupont (C)

Réseau Périnatal Aurore, Hospices Civils de Lyon, Hôpital de la Croix Rousse, Lyon, France.
Health Services and Performance Research HESPER EA 7425, Université de Lyon, University Claude Bernard Lyon 1, Lyon, France.

B Branger (B)

Réseau « Sécurité Naissance - Naître ensemble » des Pays-de-la-Loire, France.

C Crenn Hebert (C)

Louis Mourier University Hospital, APHP, Colombes, France.
Réseau Périnatal des Hauts de Seine, PERINAT92, Issy-les-Moulineaux, France.

C Huissoud (C)

Health Services and Performance Research HESPER EA 7425, Université de Lyon, University Claude Bernard Lyon 1, Lyon, France.
Maternité de la Croix Rousse, Lyon, France.

J Fresson (J)

CRESS U1153, INSERM, Obstetrical, Perinatal and Paediatric Epidemiology (EPOPé) Research Team, Université de Paris, Paris, France.
CHRU Nancy, Réseau Périnatal Lorrain, France.

N Winer (N)

Service de Gynécologie Obstétrique HME Université de Nantes, NUN, INRA, UMR 1280, Phan, Université de Nantes, Nantes, France.

B Langer (B)

CHU de Strasbourg, Strasbourg, France.

P Rozenberg (P)

CHI de Poissy, Poissy, France.

O Morel (O)

CHRU de Nancy, Nancy, France.

M P Bonnet (MP)

Anaesthesia and Critical Care department, Trousseau Hospital, APHP, Sorbonne University, Paris, France.

F Perrotin (F)

CHRU de Tours, Tours, France.

E Azria (E)

CRESS U1153, INSERM, Obstetrical, Perinatal and Paediatric Epidemiology (EPOPé) Research Team, Université de Paris, Paris, France.
Maternity Unit, Paris Saint Joseph Hospital, DHU Risks in Pregnancy, Paris Descartes University, Paris, France.

L Carbillon (L)

Réseau Périnatal NEF Naître dans l'Est Francilien, Paris 13 University, France.

C Chiesa (C)

CRESS U1153, INSERM, Obstetrical, Perinatal and Paediatric Epidemiology (EPOPé) Research Team, Université de Paris, Paris, France.

P Raynal (P)

CH de Versailles, Site Andre Mignot, Versailles, France.

R C Rudigoz (RC)

Health Services and Performance Research HESPER EA 7425, Université de Lyon, University Claude Bernard Lyon 1, Lyon, France.
Maternité de la Croix Rousse, Lyon, France.

M Dreyfus (M)

Service de Gynécologie Obstétrique et Médecine de la Reproduction, CHU de Caen, Caen Cedex, France.

F Vendittelli (F)

Réseau de Santé en Périnatalité d'Auvergne, CHU de Clermont-Ferrand, France.
CNRS, SIGMA Clermont, Institut Pascal, CHU Clermont-Ferrand, Université Clermont Auvergne, Clermont-Ferrand, France.

S Patrier (S)

CHU de Rouen, Rouen, France.

C Deneux-Tharaux (C)

CRESS U1153, INSERM, Obstetrical, Perinatal and Paediatric Epidemiology (EPOPé) Research Team, Université de Paris, Paris, France.

L Sentilhes (L)

Department of Obstetrics and Gynaecology, Bordeaux University Hospital, Bordeaux, France.

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