Multiple cutaneous fistula after titanium dental implant: A case report.
cutaneous fistula
dental implant
inflammatory reaction
titanium
Journal
Clinical implant dentistry and related research
ISSN: 1708-8208
Titre abrégé: Clin Implant Dent Relat Res
Pays: United States
ID NLM: 100888977
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
revised:
11
12
2020
received:
14
10
2020
accepted:
17
12
2020
pubmed:
5
1
2021
medline:
16
4
2021
entrez:
4
1
2021
Statut:
ppublish
Résumé
Dental implants allow functional and aesthetic reestablishment. Titanium (Ti) implants emerge as the preferred choice because Ti is considered an inert material, highly resistant to corrosion. However, virtually no material can be considered universally biocompatible and this includes titanium. To report an unusual presentation of inflammatory reaction after a Ti dental implant. The patient presented to a dermatology clinic to evaluate lesions on her face. She reported the placement of dental implants 2 years earlier, one of which evolved with inflammatory signs and instability a few days after the procedure. As anti-inflammatory and antibiotic therapy were fruitless, after 3 months the implant was removed, but the inflammation persisted. On physical examination, painful erythematous-papule-nodular lesions were found on the left mandibular and submandibular region. Culture tests for microorganisms were negative and histopathological examination revealed a chronic fistula with a foreign body reaction. Using X-ray fluorescence, Ti particles were found along the fistula wall. Professionals should be aware of complications arising from dental implants, including Ti implants. Detailed anamnesis and laboratory investigation can assure diagnosis for specific therapeutic approaches.
Sections du résumé
BACKGROUND
BACKGROUND
Dental implants allow functional and aesthetic reestablishment. Titanium (Ti) implants emerge as the preferred choice because Ti is considered an inert material, highly resistant to corrosion. However, virtually no material can be considered universally biocompatible and this includes titanium.
PURPOSE
OBJECTIVE
To report an unusual presentation of inflammatory reaction after a Ti dental implant.
MATERIALS AND METHODS
METHODS
The patient presented to a dermatology clinic to evaluate lesions on her face. She reported the placement of dental implants 2 years earlier, one of which evolved with inflammatory signs and instability a few days after the procedure. As anti-inflammatory and antibiotic therapy were fruitless, after 3 months the implant was removed, but the inflammation persisted. On physical examination, painful erythematous-papule-nodular lesions were found on the left mandibular and submandibular region.
RESULTS
RESULTS
Culture tests for microorganisms were negative and histopathological examination revealed a chronic fistula with a foreign body reaction. Using X-ray fluorescence, Ti particles were found along the fistula wall.
CONCLUSIONS
CONCLUSIONS
Professionals should be aware of complications arising from dental implants, including Ti implants. Detailed anamnesis and laboratory investigation can assure diagnosis for specific therapeutic approaches.
Substances chimiques
Dental Implants
0
Titanium
D1JT611TNE
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
270-274Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
Nicoli LG, Oliveira GJPL, Lopes BMV, Marcantonio C, Zandim-Barcelos DL, Marcantonio E Jr. Survival/success of dental implants with acid-etched surfaces: a retrospective evaluation after 8 to 10 years. Braz Dent J. 2017;28(3):330-336. https://doi.org/10.1590/0103-6440201601471.
Sicilia A, Cuesta S, Coma G, et al. Titanium allergy in dental implant patients: a clinical study on 1500 consecutive patients. Clin Oral Implants Res. 2008;19(8):823-835. https://doi.org/10.1111/j.1600-0501.2008.01544.x.
Siddiqi A, Payne AGT, de Silva RK, Duncan WJ. Titanium allergy: could it affect dental implant integration? Clin Oral Implants Res. 2011;22(7):673-680. https://doi.org/10.1111/j.1600-0501.2010.02081.x.
Liaw K, Delfini RH, Abrahams JJ. Dental implant complications. Semin Ultrasound CT MR. 2015;36(5):427-433. https://doi.org/10.1053/j.sult.2015.09.007.
Motwani MP, Gilroy DW. Macrophage development and polarization in chronic inflammation. Semin Immunol. 2015;27(4):257-266. https://doi.org/10.1016/j.smim.2015.07.002.
Aivaliotis M, Kontochristopoulos G, Hatziolou E, Aroni K, Zakopoulou N. Successful colchicine administration in facial granulomas caused by cosmetic implants: report of a case. J Dermatolog Treat. 2007;18(2):112-114. https://doi.org/10.1080/08910600601149619.
Caicedo MS, Desai R, McAllister K, Reddy A, Jacobs JJ, Hallab NJ. Soluble and particulate Co-Cr-Mo alloy implant metals activate the inflammasome danger signaling pathway in human macrophages: a novel mechanism for implant debris reactivity. J Orthop Res. 2009;27(7):847-854. https://doi.org/10.1002/jor.20826.
Abraham JÁ, Sánchez HJ, Grenón MS, Pérez CA. TXRF analysis of metals in oral fluids of patients with dental implants. X-Ray Spectrom. 2014;43:193-197. https://doi.org/10.1002/xrs.2538.
Dean MC, Spiers KM, Garrevoet J, le Cabec A. Synchrotron X-ray fluorescence mapping of Ca, Sr and Zn at the neonatal line in human deciduous teeth reflects changing perinatal physiology. Arch Oral Biol. 2019;104:90-102. https://doi.org/10.1016/j.archoralbio.2019.05.024.
Lansdown AB, Mirastschijski U, Stubbs N, Scanlon E, Agren MS. Zinc in wound healing: theoretical, experimental, and clinical aspects. Wound Repair Regen. 2007;15(1):2-16. https://doi.org/10.1111/j.1524-475X.2006.00179.x.
Hasegawa M, Saruta J, Hirota M, et al. A newly created Meso-, micro-, and nano-scale rough titanium surface promotes bone-implant integration. Int J Mol Sci. 2020;21(3):783. https://doi.org/10.3390/ijms21030783.
Hosoki M, Nishigawa K, Tajima T, Ueda M, Matsuka Y. Cross-sectional observational study exploring clinical risk of titanium allergy caused by dental implants. J Prosthodont Res. 2018;62(4):426-431. https://doi.org/10.1016/j.jpor.2018.03.003.
Yan H, Afroz S, Dalanon J, Goto N, Hosoki M, Matsuka Y. Metal allergy patient treated by titanium implant denture: a case report with at least 4-year follow-up. Clin Case Rep. 2018;6(10):1972-1977. https://doi.org/10.1002/ccr3.1753.
Mints D, Elias C, Funkenbusch P, Meirelles L. Integrity of implant surface modifications after insertion. Int J Oral Maxillofac Implants. 2014;29(1):97-104. https://doi.org/10.11607/jomi.3259.
Cooper LF. A role for surface topography in creating and maintaining bone at titanium endosseous implants. J Prosthet Dent. 2000;84(5):522-534. https://doi.org/10.1067/mpr.2000.111966.
Wilson TG Jr, Valderrama P, Burbano M, et al. Foreign bodies associated with peri-implantitis human biopsies. J Periodontol. 2015;86(1):9-15. https://doi.org/10.1902/jop.2014.140363.
Suárez-López Del Amo F, Rudek I, Wagner VP, et al. Titanium activates the DNA damage response pathway in oral epithelial cells: a pilot study. Int J Oral Maxillofac Implants. 2017;32(6):1413-1420. https://doi.org/10.11607/jomi.6077.
Javed F, Al-Hezaimi K, Almas K, Romanos GE. Is titanium sensitivity associated with allergic reactions in patients with dental implants? A systematic review. Clin Implant Dent Relat Res. 2013;15(1):47-52. https://doi.org/10.1111/j.1708-8208.2010.00330.x.
Thyssen JP, Menné T. Metal allergy: a review on exposures, penetration, genetics, prevalence, and clinical implications. Chem Res Toxicol. 2010;23(2):309-318. https://doi.org/10.1021/tx9002726.
Hosoki M, Nishigawa K, Miyamoto Y, Ohe G, Matsuka Y. Allergic contact dermatitis caused by titanium screws and dental implants. J Prosthodont Res. 2016;60(3):213-219. https://doi.org/10.1016/j.jpor.2015.12.004.
Mitchell DL, Synnott SA, VanDercreek JA. Tissue reaction involving an intraoral skin graft and CP titanium abutments: a clinical report. Int J Oral Maxillofac Implants. 1990;5(1):79-84.