Calcium-sensing receptor in the development and treatment of pulmonary hypertension.
Adamantane
/ analogs & derivatives
Animals
Autophagy
/ drug effects
Calcium
/ metabolism
Calcium Channel Blockers
/ therapeutic use
Cell Differentiation
/ drug effects
Cell Movement
/ drug effects
Cell Proliferation
/ drug effects
Endothelial Cells
/ drug effects
Gene Expression Regulation
Humans
Hypertension, Pulmonary
/ drug therapy
Myocytes, Smooth Muscle
/ drug effects
Pulmonary Artery
/ drug effects
Quinoxalines
/ therapeutic use
Receptors, Calcium-Sensing
/ antagonists & inhibitors
Signal Transduction
Vascular Remodeling
/ drug effects
Autophagy
Calcium-sensing receptor
Pulmonary arterial hypertension
Pulmonary artery smooth muscle cells
Pulmonary hypertension
Remodeling
Journal
Molecular biology reports
ISSN: 1573-4978
Titre abrégé: Mol Biol Rep
Pays: Netherlands
ID NLM: 0403234
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
12
07
2020
accepted:
03
12
2020
pubmed:
5
1
2021
medline:
21
5
2021
entrez:
4
1
2021
Statut:
ppublish
Résumé
Calcium-sensing receptor (CaSR) is widely involved in the cell proliferation, differentiation, migration, adhesion and apoptosis, which can affect the vascular remodeling in the humanbody. The main ligand of CaSR is extracellular Ca
Identifiants
pubmed: 33394231
doi: 10.1007/s11033-020-06065-3
pii: 10.1007/s11033-020-06065-3
doi:
Substances chimiques
2-quinoxaline-carboxamide-N-adamantan-1-yl
0
CASR protein, human
0
Calcium Channel Blockers
0
Quinoxalines
0
Receptors, Calcium-Sensing
0
Adamantane
PJY633525U
Calcium
SY7Q814VUP
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
975-981Subventions
Organisme : National Natural Science Foundation of China
ID : 81973404, 81503058
Organisme : Department of Education of Liaoning Province
ID : JC2019034
Organisme : Natural Science Foundation of Liaoning Province
ID : 2014021065
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