Treatment of pyoderma gangrenosum: A multicenter survey-based study assessing satisfaction and quality of life.


Journal

Dermatologic therapy
ISSN: 1529-8019
Titre abrégé: Dermatol Ther
Pays: United States
ID NLM: 9700070

Informations de publication

Date de publication:
03 2021
Historique:
revised: 04 12 2020
received: 06 10 2020
accepted: 21 12 2020
pubmed: 5 1 2021
medline: 26 5 2021
entrez: 4 1 2021
Statut: ppublish

Résumé

Pyoderma gangrenosum (PG) lacks consensus regarding treatment, and no prior studies assess treatment satisfaction in PG. The objective of this study was to determine patient-reported satisfaction in the treatment of PG, and associations with satisfaction. Methodology was a multicenter cross-sectional survey for patients who received systemic medication(s) to treat PG. Thirty-five patients completed the survey (mean age: 54.0 years, 65.7% female, response rate: 81.4%). Mean (± SD) SATMED-Q score was 75.0 (±16.2, range: 67.6-85.3). Older patients (72.6 ± 23.6 for 18-39 years, 74.4 ± 16.1 for 40-59, 77.1 ± 11.6 for 60+), plus those with higher incomes (72.9 ± 20.3 for $0-49 000; 74.0 ± 17.6 for $50 000-99 000; 79.0 ± 14.6 for $100 000+) and education status (69.4 ± 14.3 for high school equivalent, 72.9 ± 15.9 for undergraduate, 91.7 ± 10.6 for graduate), were more satisfied with treatment. Ulcerative PG had higher SATMED-Q scores (79.0 ± 13.2) than other subtypes (66.2 ± 19.3). For local therapy, wound care, or pain control, 63.2%, 100%, and 75% were satisfied, respectively. The mean DLQI was 8.6 (±7.6, range: 0-29), and higher DLQI was associated with decreased satisfaction. Satisfaction with providers was positively correlated with global satisfaction (Pearson's r = 0.638). The presence of pain and/or depression influenced both SATMED-Q (72.8 ± 18.8 with pain, 78.3 ± 11.2 without; 68.2 ± 18.8 with depression, 80.1 ± 12.2 without) and DLQI scores (12.1 ± 8.1 with pain, 3.9 ± 3.4 without; 10.3 ± 7.1 with depression, 7.4 ± 8.0 without). To optimize the patient experience, non-modifiable associations should be individually considered, and potentially modifiable associations such as satisfaction with specific providers, pain, and depression, may be targeted for management.

Identifiants

pubmed: 33394563
doi: 10.1111/dth.14736
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e14736

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

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Auteurs

Misty M Hobbs (MM)

Department of Dermatology, Mayo Clinic, Jacksonville, Florida, USA.

Rebecca Byler (R)

Department of Biomedical Engineering, Yale University, New Haven, Connecticut, USA.

Emile Latour (E)

Oregon Health & Science University, Biostatistics Shared Resource, Knight Cancer Institute, Portland, Oregon, USA.

Lauren Bonomo (L)

Division of Dermatology, University of Washington, Seattle, Washington, USA.

Kerry Hennessy (K)

Department of Dermatology and Cutaneous Surgery, University of South Florida, Tampa, Florida, USA.

Carla N Cruz-Diaz (CN)

Department of Dermatology, University of California San Francisco, San Francisco, California, USA.

Michi M Shinohara (MM)

Division of Dermatology, University of Washington, Seattle, Washington, USA.

Lucia Seminario-Vidal (L)

Department of Dermatology and Cutaneous Surgery, University of South Florida, Tampa, Florida, USA.

Kanade Shinkai (K)

Department of Dermatology, University of California San Francisco, San Francisco, California, USA.

Alex G Ortega-Loayza (AG)

Department of Dermatology, Oregon Health and Science University, Portland, Oregon, USA.

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