TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
04 01 2021
04 01 2021
Historique:
received:
11
07
2019
accepted:
20
11
2020
entrez:
5
1
2021
pubmed:
6
1
2021
medline:
15
1
2021
Statut:
epublish
Résumé
TARM1 is a member of the leukocyte immunoglobulin-like receptor family and stimulates macrophages and neutrophils in vitro by associating with FcRγ. However, the function of this molecule in the regulation of the immune system is unclear. Here, we show that Tarm1 expression is elevated in the joints of rheumatoid arthritis mouse models, and the development of collagen-induced arthritis (CIA) is suppressed in Tarm1
Identifiants
pubmed: 33397982
doi: 10.1038/s41467-020-20307-9
pii: 10.1038/s41467-020-20307-9
pmc: PMC7782728
doi:
Substances chimiques
Ligands
0
Receptors, Immunologic
0
TARM1 protein, mouse
0
enhanced green fluorescent protein
0
Green Fluorescent Proteins
147336-22-9
Granulocyte-Macrophage Colony-Stimulating Factor
83869-56-1
Collagen
9007-34-5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
94Références
Immunity. 2009 Jan 16;30(1):108-19
pubmed: 19144317
J Biol Chem. 2002 Nov 29;277(48):46197-204
pubmed: 12356768
Arthritis Res Ther. 2006;8(4):R100
pubmed: 16805906
J Immunol. 2015 Apr 1;194(7):3156-68
pubmed: 25725107
Nat Commun. 2015 Sep 25;6:8483
pubmed: 26404464
Immunity. 2011 May 27;34(5):637-50
pubmed: 21616434
Immunol Rev. 2016 Jan;269(1):162-74
pubmed: 26683152
Immunity. 2011 Feb 25;34(2):149-62
pubmed: 21349428
J Hum Genet. 2015 Nov;60(11):703-8
pubmed: 26040207
J Thromb Haemost. 2007 Nov;5(11):2274-83
pubmed: 17764536
Eur J Immunol. 2000 Jun;30(6):1568-75
pubmed: 10898492
J Clin Invest. 2011 Sep;121(9):3505-16
pubmed: 21841309
Annu Rev Immunol. 2012;30:491-529
pubmed: 22224766
Blood. 2005 May 1;105(9):3623-32
pubmed: 15650060
Trends Immunol. 2002 Feb;23(2):81-8
pubmed: 11929131
Immunity. 2002 Feb;16(2):157-68
pubmed: 11869678
J Leukoc Biol. 2008 Apr;83(4):799-803
pubmed: 18063695
Nat Genet. 2012 Dec;44(12):1336-40
pubmed: 23143596
J Exp Med. 2002 Jan 21;195(2):201-9
pubmed: 11805147
Immunol Cell Biol. 2008 Oct;86(7):580-7
pubmed: 18679407
N Engl J Med. 2011 Dec 8;365(23):2205-19
pubmed: 22150039
Nat Protoc. 2008;3(4):612-8
pubmed: 18388943
Eur J Immunol. 2018 Jan;48(1):32-38
pubmed: 29193037
Arthritis Res Ther. 2010;12(5):R188
pubmed: 20939892
Curr Opin Immunol. 2001 Jun;13(3):326-31
pubmed: 11406364
J Immunol. 2006 Mar 1;176(5):3149-56
pubmed: 16493074
Immunity. 2016 Nov 15;45(5):963-973
pubmed: 27851925
Immunol Rev. 2015 Sep;267(1):117-36
pubmed: 26284474
Blood. 2016 Feb 4;127(5):529-37
pubmed: 26552697
Arthritis Rheum. 1997 Jul;40(7):1210-8
pubmed: 9214420
Nature. 2003 Nov 27;426(6965):454-60
pubmed: 14647385
J Immunol. 1985 Oct;135(4):2443-51
pubmed: 2411796
J Immunol. 2017 Oct 15;199(8):2692-2700
pubmed: 28887430
J Immunol. 2015 Oct 1;195(7):3149-59
pubmed: 26311901
Nat Med. 2008 Feb;14(2):176-80
pubmed: 18204462
Immunol Rev. 2008 Aug;224:98-123
pubmed: 18759923
J Exp Med. 2000 Jan 17;191(2):313-20
pubmed: 10637275
Nat Protoc. 2007;2(5):1269-75
pubmed: 17546023
Transgenic Res. 2013 Feb;22(1):195-200
pubmed: 22826106
Blood. 2004 Sep 1;104(5):1386-95
pubmed: 15155468
Annu Rev Immunol. 2002;20:669-707
pubmed: 11861615
J Immunol. 2008 Feb 1;180(3):1662-9
pubmed: 18209062
J Immunol. 2015 Apr 1;194(7):3169-79
pubmed: 25725106
J Immunol. 1995 Aug 1;155(3):1588-98
pubmed: 7636219
J Exp Med. 2006 Jun 12;203(6):1419-25
pubmed: 16754721
Cell Immunol. 2014 Jan;287(1):46-52
pubmed: 24380839
Science. 1991 Aug 30;253(5023):1026-8
pubmed: 1887217
Proc Natl Acad Sci U S A. 1989 Jan;86(2):636-40
pubmed: 2463633
Matrix Biol. 2009 May;28(4):202-10
pubmed: 19345263
Immunology. 2009 May;127(1):8-17
pubmed: 19368561