Brown adipose tissue is associated with cardiometabolic health.

Adipose Tissue, Brown / metabolism Blood Glucose / metabolism Cardiovascular Diseases / metabolism Diabetes Mellitus, Type 2 / metabolism Dyslipidemias / metabolism Fluorodeoxyglucose F18 / metabolism Humans Positron Emission Tomography Computed Tomography / methods Retrospective Studies

Journal

Nature medicine
ISSN: 1546-170X
Titre abrégé: Nat Med
Pays: United States
ID NLM: 9502015

Informations de publication

Date de publication:
01 2021
Historique:
received: 14 02 2020
accepted: 09 10 2020
pubmed: 6 1 2021
medline: 20 2 2021
entrez: 5 1 2021
Statut: ppublish

Résumé

White fat stores excess energy, whereas brown and beige fat are thermogenic and dissipate energy as heat. Thermogenic adipose tissues markedly improve glucose and lipid homeostasis in mouse models, although the extent to which brown adipose tissue (BAT) influences metabolic and cardiovascular disease in humans is unclear

Identifiants

DOI: 10.1038/s41591-020-1126-7 PMID: 33398160 PMC: PMC8461455
pubmed: 33398160
doi: 10.1038/s41591-020-1126-7
pii: 10.1038/s41591-020-1126-7
pmc: PMC8461455
mid: NIHMS1737323
doi:

Substances chimiques

Blood Glucose 0
Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

58-65

Subventions

Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001866
Pays : United States
Organisme : American Diabetes Association (ADA)
ID : 1-17-ACE-17
Pays : International
Organisme : U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (NCATS)
ID : UL1TR001866
Pays : International

Commentaires et corrections

Type : CommentIn
Type : CommentIn

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Auteurs

Tobias Becher (T)

Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany.
Division of Cardiology, First Department of Medicine, University Medical Center Mannheim, Mannheim, Germany.
ORCID: 0000-0001-7670-757X

Srikanth Palanisamy (S)

Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
Weill Cornell Medicine, New York, NY, USA.

Daniel J Kramer (DJ)

Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
Weill Cornell Medicine, New York, NY, USA.
Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.

Mahmoud Eljalby (M)

Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
Weill Cornell Medicine, New York, NY, USA.
ORCID: 0000-0003-4951-7257

Sarah J Marx (SJ)

Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.

Andreas G Wibmer (AG)

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Scott D Butler (SD)

Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.

Caroline S Jiang (CS)

Center for Clinical and Translational Science, The Rockefeller University, New York, NY, USA.

Roger Vaughan (R)

Weill Cornell Medicine, New York, NY, USA.
Center for Clinical and Translational Science, The Rockefeller University, New York, NY, USA.

Heiko Schöder (H)

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Allyn Mark (A)

Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

Paul Cohen (P)

Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA. pcohen@rockefeller.edu.
ORCID: 0000-0002-2786-8585

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Classifications MeSH

questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Tissu adipeux brun › Brown adipose tissue is associated with...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Glycémie › Brown adipose tissue is associated with...
questionsmedicales.fr › Maladies cardiovasculaires › Brown adipose tissue is associated with...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabète de type 2 › Brown adipose tissue is associated with...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles du métabolisme lipidique › Dyslipidémies › Brown adipose tissue is associated with...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › Brown adipose tissue is associated with...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Brown adipose tissue is associated with...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Tomographie par émission de positons couplée à la tomodensitométrie › Brown adipose tissue is associated with...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Brown adipose tissue is associated with...