[Association between cognitive impairment and depression in Chilean older adults].
Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores.
Journal
Revista medica de Chile
ISSN: 0717-6163
Titre abrégé: Rev Med Chil
Pays: Chile
ID NLM: 0404312
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
30
11
2018
accepted:
23
06
2020
entrez:
5
1
2021
pubmed:
6
1
2021
medline:
29
1
2021
Statut:
ppublish
Résumé
Depression has been previously associated with cognitive impairment in high income country populations. However, its association in the Chilean population has not been investigated. To investigate the association between depression and cognitive impairment. Data from 1384 Chilean adults aged > 60 years, participating in the National Health Survey 2009-2010 was analyzed. Cognitive impairment was assessed using the Mini Mental Examination score. The medical diagnosis of depression was self-reported. The association between depression and cognitive impairment was assessed using a logistic regression. Depression was positively associated with cognitive impairment. However, the magnitude of the association was higher in men (Odds ratio (OR) = 4.02 [95% confidence intervals (CI): 1.44; 6.61], p < 0.01]) than in women (OR = 2.23 [95%CI: 1.03; 3.43], p = 0.04). Older adults who were diagnosed for the first time with depression after 65 years of age, showed a stronger association with cognitive impairment (OR = 6.65 [95% CI: 2.39; 10.9], p < 0.01) than those diagnosed before 55 years. Our study confirms the association between depression and cognitive impairment. Further research is needed to elucidate the nature and potential mechanisms that link depression with cognitive impairment.
Sections du résumé
BACKGROUND
BACKGROUND
Depression has been previously associated with cognitive impairment in high income country populations. However, its association in the Chilean population has not been investigated.
AIM
OBJECTIVE
To investigate the association between depression and cognitive impairment.
MATERIAL AND METHODS
METHODS
Data from 1384 Chilean adults aged > 60 years, participating in the National Health Survey 2009-2010 was analyzed. Cognitive impairment was assessed using the Mini Mental Examination score. The medical diagnosis of depression was self-reported. The association between depression and cognitive impairment was assessed using a logistic regression.
RESULTS
RESULTS
Depression was positively associated with cognitive impairment. However, the magnitude of the association was higher in men (Odds ratio (OR) = 4.02 [95% confidence intervals (CI): 1.44; 6.61], p < 0.01]) than in women (OR = 2.23 [95%CI: 1.03; 3.43], p = 0.04). Older adults who were diagnosed for the first time with depression after 65 years of age, showed a stronger association with cognitive impairment (OR = 6.65 [95% CI: 2.39; 10.9], p < 0.01) than those diagnosed before 55 years.
CONCLUSIONS
CONCLUSIONS
Our study confirms the association between depression and cognitive impairment. Further research is needed to elucidate the nature and potential mechanisms that link depression with cognitive impairment.
Identifiants
pubmed: 33399679
pii: S0034-98872020000700947
doi: 10.4067/S0034-98872020000700947
pii:
doi:
Types de publication
Journal Article
Langues
spa
Sous-ensembles de citation
IM