Evaluation of phage adsorption to Salmonella Typhimurium exposed to different levels of pH and antibiotic.

Adsorption Anti-Bacterial Agents / pharmacology Bacteriophages Ciprofloxacin / pharmacology Salmonella typhimurium
Antibiotic resistance Lytic activity Phage adsorption Phage therapy Salmonella

Journal

Microbial pathogenesis
ISSN: 1096-1208
Titre abrégé: Microb Pathog
Pays: England
ID NLM: 8606191

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 10 12 2020
revised: 23 12 2020
accepted: 27 12 2020
pubmed: 6 1 2021
medline: 22 6 2021
entrez: 5 1 2021
Statut: ppublish

Résumé

This study was designed to evaluate the physicochemical properties of phage P22 in different pH and antibiotic levels as measured by growth kinetics, phage adsorption, and lytic activity. P22 was susceptible to acidic pHs and stable above pH 4. The latent period of P22 was 45 min and burst size was 34 phages/cell. The adsorption ability of phage to Salmonella Typhimurium was varied depending on the multiplicity of infections (MOIs). The latent period was reduced to 6.84, 4.02, and 1.72 h, respectively, on the levels of the host at 10

Identifiants

DOI: 10.1016/j.micpath.2020.104726 PMID: 33400986
pubmed: 33400986
pii: S0882-4010(20)31092-5
doi: 10.1016/j.micpath.2020.104726
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Ciprofloxacin 5E8K9I0O4U

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104726

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Gibeom Jeon (G)

Department of Biomedical Science and Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.

Juhee Ahn (J)

Department of Biomedical Science and Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea. Electronic address: juheeahn@kangwon.ac.kr.

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Adsorption › Evaluation of phage adsorption to Salmonella...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Evaluation of phage adsorption to Salmonella...
questionsmedicales.fr › Virus › Bactériophages › Evaluation of phage adsorption to Salmonella...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Quinolinone › Fluoroquinolones › Ciprofloxacine › Evaluation of phage adsorption to Salmonella...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Salmonella › Salmonella enterica › Salmonella typhimurium › Evaluation of phage adsorption to Salmonella...