Spontaneous regression of lung metastases in hepatocellular carcinoma: A case report.

Hepatocellular carcinoma Lung metastasis Spontaneous regression

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 27 11 2020
revised: 14 12 2020
accepted: 15 12 2020
pubmed: 6 1 2021
medline: 6 1 2021
entrez: 5 1 2021
Statut: ppublish

Résumé

Spontaneous regression of hepatocellular carcinoma (HCC) is a rare condition. However, although there have been multiple reports of spontaneous regression, the definitive pathogenic mechanism of this phenomenon is still unclear. We encountered a case of a 78-year-old man who was undergoing dialysis for end-stage kidney disease with hepatitis C virus-associated chronic hepatitis presenting with HCC. The patient had previously undergone right lobectomy of the liver, but the cancer recurred with multiple lung metastases after 5 months. Approximately 13 months after the initial diagnosis of recurrence, the lung metastases decreased in size and eventually resolved without any anticancer therapy. The patient remains alive for over 41 months after recurrence. Based on our case and literature, Hypoxia with hypotension due to hemodialysis can reduce the blood and oxygen supply of the body, which may lead to the spontaneous regression of the metastatic tumors. We herein reported a case of spontaneous regression of HCC undergoing dialysis.

Identifiants

DOI: 10.1016/j.ijscr.2020.12.045 PMID: 33401194 PMC: PMC7787914
pubmed: 33401194
pii: S2210-2612(20)31235-9
doi: 10.1016/j.ijscr.2020.12.045
pmc: PMC7787914
pii:
doi:

Types de publication

Case Reports

Langues

eng

Pagination

378-381

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Daisuke Muroya (D)

Department of Surgery, Kurume University, 67 Asahimachi, Kurume, Fukuoka Prefecture, 830-0003, Japan. Electronic address: muroya_daisuke@med.kurume-u.ac.jp.

Toshihiro Sato (T)

Department of Surgery, Kurume University, 67 Asahimachi, Kurume, Fukuoka Prefecture, 830-0003, Japan. Electronic address: toshihiro_sato@med.kurume-u.ac.jp.

Hisamune Sakai (H)

Department of Surgery, Kurume University, 67 Asahimachi, Kurume, Fukuoka Prefecture, 830-0003, Japan. Electronic address: hisamune_sakai@med.kurume-u.ac.jp.

Toru Hisaka (T)

Department of Surgery, Kurume University, 67 Asahimachi, Kurume, Fukuoka Prefecture, 830-0003, Japan. Electronic address: toru_hisaka@med.kurume-u.ac.jp.

Yoshito Akagi (Y)

Department of Surgery, Kurume University, 67 Asahimachi, Kurume, Fukuoka Prefecture, 830-0003, Japan. Electronic address: yoshito_akagi@med.kurume-u.ac.jp.

Koji Okuda (K)

Department of Surgery, Kurume University, 67 Asahimachi, Kurume, Fukuoka Prefecture, 830-0003, Japan. Electronic address: koji_okuda@med.kurume-u.ac.jp.

Classifications MeSH