Micropapillary Bladder Cancer Metastatic to the Breast: A Case Report and Brief Literature Review.
Metastasis
breast cancer
immunotherapy
neoadjuvant therapy
urothelial cancer
Journal
In vivo (Athens, Greece)
ISSN: 1791-7549
Titre abrégé: In Vivo
Pays: Greece
ID NLM: 8806809
Informations de publication
Date de publication:
Historique:
received:
24
09
2020
revised:
14
10
2020
accepted:
15
10
2020
entrez:
6
1
2021
pubmed:
7
1
2021
medline:
22
6
2021
Statut:
ppublish
Résumé
Bladder cancer (BC) usually metastasizes to the lymph nodes, bone, lung, liver and peritoneum, but rarely in the breast. We present a case of a 66-year-old female diagnosed with a massive bladder tumor, who presented a right mammary nodule after neo-adjuvant chemotherapy. A biopsy of the nodule did not permit a definite diagnosis of metastatic spread, which was confirmed by excision of the nodule. In the literature, we found only 7 other similar cases of BC metastasis to the breast. Currently, a non-invasive method for differentiating a breast metastasis from primary cancer is lacking, although there are some clinical and radiological aspects that may help the diagnosis. Histological examination provides diagnostic certainty. Breast metastases from BC are unusual and consequently difficult to identify without non-invasive tools. Clinical history and histological study play a pivotal role in determining the correct diagnosis.
Sections du résumé
BACKGROUND
BACKGROUND
Bladder cancer (BC) usually metastasizes to the lymph nodes, bone, lung, liver and peritoneum, but rarely in the breast.
CASE REPORT
METHODS
We present a case of a 66-year-old female diagnosed with a massive bladder tumor, who presented a right mammary nodule after neo-adjuvant chemotherapy. A biopsy of the nodule did not permit a definite diagnosis of metastatic spread, which was confirmed by excision of the nodule. In the literature, we found only 7 other similar cases of BC metastasis to the breast. Currently, a non-invasive method for differentiating a breast metastasis from primary cancer is lacking, although there are some clinical and radiological aspects that may help the diagnosis. Histological examination provides diagnostic certainty.
CONCLUSION
CONCLUSIONS
Breast metastases from BC are unusual and consequently difficult to identify without non-invasive tools. Clinical history and histological study play a pivotal role in determining the correct diagnosis.
Identifiants
pubmed: 33402496
pii: 35/1/453
doi: 10.21873/invivo.12278
pmc: PMC7880790
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
453-459Informations de copyright
Copyright© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
Références
Korean J Radiol. 2014 Jan-Feb;15(1):20-8
pubmed: 24497788
Radiology. 1982 Jul;144(2):309-12
pubmed: 7089284
Cancer. 1972 Jun;29(6):1691-6
pubmed: 4337956
J Clin Oncol. 2001 Feb 1;19(3):666-75
pubmed: 11157016
AJR Am J Roentgenol. 1977 Oct;129(4):673-6
pubmed: 409241
Am J Surg Pathol. 2010 Sep;34(9):1367-76
pubmed: 20717002
Eur J Cancer. 2013 Apr;49(6):1374-403
pubmed: 23485231
Pathol Res Pract. 2000;196(1):35-9
pubmed: 10674270
Eur Urol. 2005 Aug;48(2):202-5; discussion 205-6
pubmed: 15939524
J Clin Oncol. 2011 Jun 1;29(16):2171-7
pubmed: 21502557
AJR Am J Roentgenol. 2011 Jan;196(1):117-22
pubmed: 21178055
Am J Clin Pathol. 1989 Jul;92(1):27-35
pubmed: 2750705
Am J Clin Pathol. 2012 Jul;138(1):57-64
pubmed: 22706858
AJR Am J Roentgenol. 1983 Oct;141(4):685-90
pubmed: 6604418
Adv Urol. 2011;2011:217153
pubmed: 22007200
J Urol. 2005 Jul;174(1):14-20
pubmed: 15947569
Pediatr Hematol Oncol. 1996 May-Jun;13(3):277-85
pubmed: 8735345
AJR Am J Roentgenol. 1997 Feb;168(2):511-2
pubmed: 9016237
J Surg Oncol. 2010 Feb 1;101(2):137-40
pubmed: 20082359
Pathology. 2008 Jun;40(4):345-51
pubmed: 18446623
Eur J Cancer. 2000 Jul;36 Suppl 2:13-6
pubmed: 10908843
Technol Health Care. 2018;26(S1):361-377
pubmed: 29758961
J Surg Oncol. 1989 Dec;42(4):264-6
pubmed: 2556613
Adv Anat Pathol. 2004 Nov;11(6):297-303
pubmed: 15505530
Eur Urol. 2016 Oct;70(4):611-620
pubmed: 26988609
Cancer. 2007 Jul 1;110(1):62-7
pubmed: 17542024
Eur Urol. 2018 Apr;73(4):543-557
pubmed: 29122377
Mod Pathol. 2013 Mar;26(3):343-9
pubmed: 23174933
Acta Cytol. 1987 May-Jun;31(3):291-300
pubmed: 3473862