Clinical and Radiological Study of Serum Fluoride in Relation to Knee Osteoarthritis.
arthritis
fluorosis
knee
Journal
Malaysian orthopaedic journal
ISSN: 1985-2533
Titre abrégé: Malays Orthop J
Pays: Malaysia
ID NLM: 101564672
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
entrez:
6
1
2021
pubmed:
7
1
2021
medline:
7
1
2021
Statut:
ppublish
Résumé
Fluorosis has been associated with an increased risk of degenerative changes in the knee. Multiple studies have found an association between arthritis and elevated fluoride levels. We aim to delineate if elevated fluoride level has any direct correlation with the degree of radiological grading and clinical symptoms in knee arthritis. A cross-sectional study of 80 knee arthritis patients was conducted from February 2017 to April 2018. Serum fluoride levels were measured and patient's pain scores, WOMAC scores and radiological grading were correlated with the elevated fluoride levels. In our study, 30 out of 80 patients had increased serum fluoride level. Statistically significant differences were noted in VAS score, WOMAC score and Kellgren and Lawrence radiological grades between patients with normal serum fluoride level and those with elevated fluoride level. There is an increased risk of knee arthritis in patients with elevated blood fluoride levels and patients with increased fluoride levels are associated with more severe symptoms and radiographic disease.
Identifiants
pubmed: 33403076
doi: 10.5704/MOJ.2011.023
pmc: PMC7751991
doi:
Types de publication
Journal Article
Langues
eng
Pagination
151-154Informations de copyright
© 2020 Malaysian Orthopaedic Association (MOA). All Rights Reserved.
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