Electrocardiogram Heart Rate as a Predictor of Severity in Acute Alcohol-Related Pancreatitis With Alcohol Withdrawal Syndrome.
acute pancreatitis
alcohol
alcohol withdrawal syndrome
ecg changes
severity scoring
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
28 Nov 2020
28 Nov 2020
Historique:
entrez:
6
1
2021
pubmed:
7
1
2021
medline:
7
1
2021
Statut:
epublish
Résumé
Background The severity of acute alcohol-related pancreatitis (AAP) with alcohol withdrawal syndrome (AWS) has not been studied. Electrocardiogram (ECG) has not been used as a predictor of severity in patients with AWS and acute pancreatitis. Objectives The study aimed to determine whether the ECG heart rate (HR) could predict the severity of AAP; secondarily, whether AWS influenced the severity of AAP based on Acute Physiology and Chronic Health Evaluation (APACHE) II and Bedside Index for Severity in Acute Pancreatitis (BISAP). Methods Demographics, comorbid illnesses, AWS, biochemistry, ECG, arterial blood gases, and CT findings were noted in patients with AAP. The severity of pancreatitis was scored into mild, moderate, and severe based on CT. BISAP, APACHE II, and ECG heart rate-APACHE (E-APACHE) were compared in patients with and without AWS. A receiver operating characteristic curve was used to find the best predictor of severity. Results Among 138 patients (M=128), 94 had AWS. ECG changes (≥1) were seen in 50%. Patients with AWS were younger, had consumed alcohol for a shorter duration, had higher systemic inflammatory response syndrome (SIRS), APACHE II, and E-APACHE II scores. APACHE II and E-APACHE II correlated significantly with severity grading, HR, alcohol duration, and AWS. HR was the best predictor of severe pancreatitis; E-APACHE was the best predictor for moderately severe pancreatitis. Conclusions Mostly, AAP appears to be mild; >2/3
Identifiants
pubmed: 33403169
doi: 10.7759/cureus.11737
pmc: PMC7773298
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e11737Informations de copyright
Copyright © 2020, Viswanathan et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Kaohsiung J Med Sci. 2010 Apr;26(4):200-5
pubmed: 20434101
J Gastroenterol Hepatol. 2001 Sep;16(9):1055-9
pubmed: 11595073
Indian Heart J. 2013 Jul-Aug;65(4):474-7
pubmed: 23993014
Dig Dis Sci. 2014 Oct;59(10):2557-64
pubmed: 24821463
J Assoc Physicians India. 2018 Mar;66(3):22-4
pubmed: 30341863
J Gastroenterol Hepatol. 2012 Oct;27(10):1576-80
pubmed: 22849657
World J Gastroenterol. 2009 Mar 28;15(12):1427-30
pubmed: 19322914
Int J Health Sci (Qassim). 2015 Oct;9(4):410-7
pubmed: 26715920
World J Emerg Surg. 2019 Jun 13;14:27
pubmed: 31210778
Postgrad Med J. 2019 Jun;95(1124):328-333
pubmed: 31123175
Gastroenterol Nurs. 2012 Jul-Aug;35(4):256-60
pubmed: 22847284
J Gastroenterol Hepatol. 2010 Dec;25(12):1816-26
pubmed: 21091991
J Prim Care Community Health. 2011 Jul 1;2(3):163-6
pubmed: 23804796
Gut. 2017 Nov;66(11):2024-2032
pubmed: 28838972
Scand J Gastroenterol. 2005 Oct;40(10):1235-9
pubmed: 16265780
Cureus. 2020 Feb 10;12(2):e6943
pubmed: 32190494
Turk J Gastroenterol. 2014 Dec;25 Suppl 1:59-62
pubmed: 25910369
J Crit Care. 2011 Apr;26(2):225.e11-8
pubmed: 21185146