Silicon-rhodamine isothiocyanate for fluorescent labelling.


Journal

Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995

Informations de publication

Date de publication:
28 01 2021
Historique:
pubmed: 7 1 2021
medline: 7 1 2021
entrez: 6 1 2021
Statut: ppublish

Résumé

An efficient synthesis for silicon-rhodamines was developed, enabling the preparation and evaluation of silicon-rhodamine isothiocyanate (SITC) as a novel tool for facile fluorescent labeling. Ease of use in conjugation to amino groups, high stability and excellent photophysical properties are demonstrated. SITC-actin was found to be neutral to F-actin polymerization induction and well suited for high resolution fluorescence microscopy.

Identifiants

pubmed: 33406188
doi: 10.1039/d0ob02016h
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

574-578

Auteurs

Veselin Nasufović (V)

Friedrich-Schiller-University, Institute of Organic Chemistry and Macromolecular Chemistry, Humboldtstr. 10, 07743 Jena, Germany. hd.arndt@uni-jena.de.

Patrick Then (P)

Leibniz-Institut of Photonic Technologies (Leibniz-IPHT), Albert-Einstein-Str. 9, 07745 Jena, Germany.

Fabian Dröge (F)

Friedrich-Schiller-University, Institute of Physical Chemistry, Helmholtzweg 4, 07743 Jena, Germany.

Michael Duong (M)

Friedrich-Schiller-University, Institute of Organic Chemistry and Macromolecular Chemistry, Humboldtstr. 10, 07743 Jena, Germany. hd.arndt@uni-jena.de.

Christoph Kaether (C)

Leibniz-Institute on Aging - Fritz Lipmann Institute (FLI), Beutenbergstr. 11, 07745 Jena, Germany.

Benjamin Dietzek (B)

Leibniz-Institut of Photonic Technologies (Leibniz-IPHT), Albert-Einstein-Str. 9, 07745 Jena, Germany and Friedrich-Schiller-University, Institute of Physical Chemistry, Helmholtzweg 4, 07743 Jena, Germany.

Rainer Heintzmann (R)

Leibniz-Institut of Photonic Technologies (Leibniz-IPHT), Albert-Einstein-Str. 9, 07745 Jena, Germany and Friedrich-Schiller-University, Institute of Physical Chemistry, Helmholtzweg 4, 07743 Jena, Germany.

Hans-Dieter Arndt (HD)

Friedrich-Schiller-University, Institute of Organic Chemistry and Macromolecular Chemistry, Humboldtstr. 10, 07743 Jena, Germany. hd.arndt@uni-jena.de.

Classifications MeSH